SCHEMBL12126752

SCHEMBL12126752

CC1(C)OB(c2ccc3c(-c4cc5ccccc5c5ccccc45)cc4c5ccccc5c(-c5cc6ccccc6c6ccccc56)cc4c3c2)OC1(C)C

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPL P06858 10/20 0.49
LIPG Q9Y5X9 10/20 0.49
PRMT5 O14744 1/20 0.41
WDR77 Q9BQA1 1/20 0.41
EGFR P00533 2/20 0.38
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36
IRAK4 Q9NWZ3 1/20 0.36
CYP11B1 P15538 1/20 0.36
P4HB P07237 1/20 0.35
CSF1R P07333 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16837490 0.89 LIPG (0.54) LPLLIPGPRMT5WDR77IDO1
SCHEMBL12126755 0.89 LIPG (0.47) LPLLIPGPRMT5WDR77EGFR
SCHEMBL311849 0.87 LPL (0.56) LPLLIPGPRMT5WDR77EGFR
SCHEMBL2015694 0.87 LPL (0.56) LPLLIPGPRMT5WDR77EGFR
SCHEMBL21764502 0.87 LPL (0.56) LPLLIPGPRMT5WDR77EGFR
SCHEMBL29787170 0.87 LPL (0.56) LPLLIPGPRMT5WDR77EGFR
SCHEMBL17548647 0.87 LPL (0.56) LPLLIPGPRMT5WDR77EGFR
SCHEMBL15456760 0.87 LPL (0.56) LPLLIPGPRMT5WDR77EGFR
SCHEMBL16837492 0.87 LIPG (0.53) LPLLIPGPRMT5WDR77IDO1
SCHEMBL25822924 0.87 LPL (0.49) LPLLIPGPRMT5WDR77EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580400-B2 Bichrysene compound and organic light emitting device having the compound CANON KABUSHIKI KAISHA (JP) 2013-11-12 US disclosed
US-8580400-B2 Bichrysene compound and organic light emitting device having the compound CANON KABUSHIKI KAISHA (JP) 2013-11-12 US disclosed
US-20110272683-A1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-11-10 US disclosed
US-20110272683-A1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110272683-A1 NOVEL BICHRYSENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND PPOX, CRY1, OXER1 LPL 2855/4885LIPG 3410/4885PRMT5 4674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.