SCHEMBL12127001

SCHEMBL12127001

CCN(CC)CCN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(CCN(CC)CC)C5=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 7/20 0.71
▸ STAT3 P40763 1/20 0.63
▸ HIF1A Q16665 1/20 0.63
▸ MEN1 O00255 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ CYP1A2 P05177 1/20 0.54
▸ POLB P06746 1/20 0.54
▸ TNNI3 P19429 1/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ STAT6 P42226 1/20 0.54
▸ TNNT2 P45379 1/20 0.54
▸ TNNC1 P63316 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ MAOB P27338 4/20 0.52
▸ BCHE P06276 2/20 0.46
▸ ACHE P22303 2/20 0.46
▸ APP P05067 1/20 0.46
▸ HEXA P06865 1/20 0.45
▸ HEXB P07686 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12225934 0.95 TERT (0.66) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL24401821 0.91 STAT3 (0.73) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL30272534 0.90 TERT (0.59) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL1105127 0.89 TERT (0.69) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL3293599 0.87 POLB (0.58) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL34460907 0.84 TERT (0.82) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL22851893 0.83 TERT (1.00) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL34460908 0.83 TERT (0.65) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL11922532 0.82 STAT3 (0.60) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL8680446 0.81 TERT (0.67) TERTSTAT3HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580143-B2 Lyotropic chromonic liquid crystal composition, method for manufacture of lyotropic chromonic liquid crystal coating film, and lyotropic chromonic liquid crystal coating film manufactured thereby KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2013-11-12 — — US disclosed
US-8580143-B2 Lyotropic chromonic liquid crystal composition, method for manufacture of lyotropic chromonic liquid crystal coating film, and lyotropic chromonic liquid crystal coating film manufactured thereby KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2013-11-12 — — US disclosed
US-20110272629-A1 LYOTROPIC CHROMONIC LIQUID CRYSTAL COMPOSITION, METHOD FOR MANUFACTURE OF LYOTROPIC CHROMONIC LIQUID CRYSTAL COATING FILM, AND LYOTROPIC CHROMONIC LIQUID CRYSTAL COATING FILM MANUFACTURED THEREBY INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY (KR) 2011-11-10 — — US disclosed
US-20110272629-A1 LYOTROPIC CHROMONIC LIQUID CRYSTAL COMPOSITION, METHOD FOR MANUFACTURE OF LYOTROPIC CHROMONIC LIQUID CRYSTAL COATING FILM, AND LYOTROPIC CHROMONIC LIQUID CRYSTAL COATING FILM MANUFACTURED THEREBY INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY (KR) 2011-11-10 — — US disclosed
US-7943208-B2 Materials and methods for the preparation of anisotropically-ordered solids BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2011-05-17 — — US disclosed
US-20100108959-A1 MATERIALS AND METHODS FOR THE PREPARATION OF ANISOTROPICALLY-ORDERED SOLIDS BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO 2010-05-06 — — US disclosed
US-7625497-B2 Materials and methods for the preparation of anisotropically-ordered solids BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) 2009-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100108959-A1 MATERIALS AND METHODS FOR THE PREPARATION OF ANISOTROPICALLY-ORDERED SOLIDS KIF23, VIM, INCENP TERT 910/4885STAT3 4185/4885HIF1A 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback