Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12391597 | 0.75 | ALDH1A1 (0.56) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL366594 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRKCNJ1KMT2AMEN1 | |
| SCHEMBL14876861 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRKCNJ1KMT2AMEN1 | |
| SCHEMBL11230056 | 0.71 | HSP90AA1 (0.33) | KMT2ATDP2NSD2HSP90AA1PAX8 | |
| SCHEMBL548391 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TSHRKCNJ1KMT2AMEN1 | |
| SCHEMBL7180797 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHRKCNJ1KMT2AMEN1 | |
| SCHEMBL6438818 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TSHRKCNJ1KMT2AMEN1 | |
| SCHEMBL3065272 | 0.70 | ERN1 (0.46) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL150283 | 0.70 | CYP3A4 (0.35) | ALDH1A1TSHRKMT2ATHRBTDP1 | |
| SCHEMBL692622 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TSHRKCNJ1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | GRAND PHARMA (CHINA) CO., LTD. (CN) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099754-A1 | 5,6-DIMETHYL XANTHONE-4-ACETIC ACID DERIVATIVES AND METHOD OF PREPARING THE SAME | HCAR2, HAO2, HK2 | ALDH1A1 1863/4885TSHR 742/4885KCNJ1 2766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.