Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.54 |
| ▸ | PYCR1 | P32322 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297585 | 0.94 | PYCR1 (0.59) | HRH3PYCR1CHRNB2CHRNA4NPSR1 | |
| SCHEMBL12679030 | 0.86 | HRH3 (0.64) | HRH3PYCR1TAAR1CYP19A1NPSR1 | |
| SCHEMBL12763726 | 0.84 | CHRNB2 (0.56) | HRH3PYCR1CHRNB2CHRNA4KDM4E | |
| SCHEMBL19496866 | 0.82 | NMT1 (0.46) | TAAR1CHRNB2CHRNA4HDAC1 | |
| SCHEMBL16312619 | 0.82 | PYCR1 (0.65) | HRH3PYCR1TAAR1NPSR1KDM4E | |
| SCHEMBL12680478 | 0.81 | HRH3 (0.75) | HRH3PYCR1TAAR1CYP19A1KDM4E | |
| SCHEMBL18993483 | 0.81 | TAAR1 (0.45) | PYCR1TAAR1CHRNB2CHRNA4CYP19A1 | |
| SCHEMBL260357 | 0.80 | HRH3 (0.81) | HRH3PYCR1TAAR1CYP19A1ALDH1A1 | |
| SCHEMBL12910454 | 0.78 | CHRNB2 (0.50) | HRH3PYCR1TAAR1CHRNB2CHRNA4 | |
| SCHEMBL4400864 | 0.76 | CYP2C19 (0.58) | HRH3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110286777-A1 | LUBRICANT AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME | RICOH COMPANY, LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110286777-A1 | LUBRICANT AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME | RICOH COMPANY, LTD. (JP) | 2011-11-24 | — | — | US | disclosed |