SCHEMBL12150754

SCHEMBL12150754

O=P(c1ccccc1)(c1cccc(-c2cccc(N(c3ccccc3)c3ccccc3)n2)n1)c1cccc(-c2cccc(N(c3ccccc3)c3ccccc3)n2)n1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
FBP1 P09467 1/20 0.33
KCNA5 P22460 2/20 0.32
HTT P42858 2/20 0.31
RECQL P46063 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
KCNN4 O15554 1/20 0.30
MAPT P10636 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12150784 0.97 LMNA (0.34) LMNAFBP1KCNA5HTTRECQL
SCHEMBL12150719 0.92 FBP1 (0.35) FBP1HTTALDH1A1TDP1MEN1
SCHEMBL2735501 0.91 KCNA5 (0.35) LMNAKCNA5HTTRECQLALDH1A1
SCHEMBL12150733 0.88 ALDH1A1 (0.35) LMNAKCNA5HTTRECQLALDH1A1
SCHEMBL12150761 0.88 KCNA5 (0.35) LMNAKCNA5HTTRECQLALDH1A1
SCHEMBL12150775 0.85 ALDH1A1 (0.35) LMNAKCNA5HTTRECQLALDH1A1
SCHEMBL185649 0.82 MEN1 (0.36) KCNA5HTTALDH1A1TDP1MAPT
SCHEMBL12150926 0.82 FBP1 (0.35) LMNAFBP1KCNA5HTTALDH1A1
SCHEMBL12150873 0.82 FBP1 (0.35) FBP1HTTALDH1A1TDP1MAPT
SCHEMBL12150728 0.82 LMNA (0.32) LMNAKCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722208-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-05-13 US disclosed
US-8722208-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-05-13 US disclosed
US-20110284828-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-11-24 US disclosed
US-20110284828-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-11-24 US disclosed