SCHEMBL12152192

SCHEMBL12152192

Cc1cc(C)c(O)c(-c2nc(-c3ccc(N(C)C)cc3)c(-c3ccc(N(C)C)cc3)n2C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 4/20 0.41
KDM4E B2RXH2 2/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
GFER P55789 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
APP P05067 2/20 0.37
FABP4 P15090 2/20 0.36
FABP5 Q01469 1/20 0.36
TEK Q02763 3/20 0.36
RAD51 Q06609 2/20 0.35
MAPK13 O15264 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13899814 0.85 NPC1 (0.45) MAPK14KDM4ENPC1ALDH1A1LMNA
SCHEMBL12152230 0.77 ALDH1A1 (0.47) MAPK14KDM4ENPC1ALDH1A1LMNA
SCHEMBL14445889 0.76 TUBB4A (0.43) MAPK14KDM4ENPC1ALDH1A1LMNA
SCHEMBL12152208 0.74 FABP4 (0.39) KDM4ENPC1ALDH1A1LMNATP53
SCHEMBL12152199 0.73 MAPK14 (0.40) MAPK14KDM4ENPC1ALDH1A1LMNA
SCHEMBL12152191 0.73 NOX1 (0.55) MAPK14KDM4EALDH1A1TP53MAPT
SCHEMBL14446726 0.73 MAPK14 (0.42) MAPK14KDM4ENPC1ALDH1A1LMNA
SCHEMBL14515668 0.72 ALDH1A1 (0.48) KDM4ENPC1ALDH1A1LMNATP53
SCHEMBL12152207 0.71 KDM4E (0.43) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL12152123 0.71 BRD4 (0.36) MAPK14KDM4ENPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999430-B2 Method of manufacturing display element KONICA MINOLTA HOLDINGS, INC. (JP) 2015-04-07 US disclosed
US-8384982-B2 Display element KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-26 US disclosed
US-8049948-B2 Process for producing electrochemical display element and electrochemical display element KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-01 US disclosed
US-8014056-B2 Display element and method of driving the same KONICA MINOLTA HOLDINGS, INC. (JP) 2011-09-06 US disclosed
US-8004742-B2 Electrochromic display device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-08-23 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-20100213813-A1 DISPLAY ELEMENT EDISON INNOVATIONS LLC 2010-08-26 US disclosed
US-20100166946-A1 METHOD OF MANUFACTURING DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2010-07-01 US disclosed
US-20100134864-A1 PROCESS FOR PRODUCING ELECTROCHEMICAL DISPLAY ELEMENT AND ELECTROCHEMICAL DISPLAY ELEMENT KONICA MINOLTA HOLDINGS ,INC. (JP) 2010-06-03 US disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-20090316249-A1 ELECTROCHROMIC DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-24 US disclosed
US-7619803-B2 Electrochromic display element and full-color electrochromic display element KONICA MINOLTA HOLDINGS, INC. (JP) 2009-11-17 US disclosed
US-20090027757-A1 ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-01-29 US disclosed