Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12168180 | 0.88 | PARP1 (0.44) | PARP1ALDH1A1POLBHPGDALOX12 | |
| SCHEMBL12168178 | 0.86 | PARP1 (0.42) | PARP1ALDH1A1POLBHPGDALOX12 | |
| SCHEMBL12168064 | 0.83 | MAPT (0.48) | ALDH1A1POLBHPGDALOX12KDM4E | |
| SCHEMBL12168199 | 0.83 | GRM2 (0.41) | PARP1ALDH1A1POLBHPGDALOX12 | |
| SCHEMBL12168144 | 0.83 | GRM2 (0.41) | PARP1ALDH1A1POLBHPGDALOX12 | |
| SCHEMBL12167195 | 0.82 | MEN1 (0.44) | PARP1ALDH1A1POLBHPGDALOX12 | |
| SCHEMBL12168185 | 0.81 | SHMT2 (0.45) | PARP1ALDH1A1POLBHPGDKDM4E | |
| SCHEMBL12167214 | 0.81 | ALDH1A1 (0.56) | ALDH1A1POLBHPGDALOX12KDM4E | |
| SCHEMBL12188167 | 0.80 | GRM5 (0.43) | PARP1ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL12167209 | 0.80 | MEN1 (0.43) | PARP1ALDH1A1POLBHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250339444-A1 | Methods and Compositions for Treating Fatty Liver and Viral Infections | UNIV LELAND STANFORD JUNIOR (US) | 2025-11-06 | — | — | US | disclosed |
| EP-4525853-A1 | METHODS AND COMPOSITIONS FOR TREATING FATTY LIVER AND VIRAL INFECTIONS | The Board of Trustees of the Leland Stanford Junior University (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-119486727-A | Methods and compositions for treating fatty liver and viral infections | 小利兰·斯坦福大学托管委员会 | 2025-02-18 | — | — | CN | disclosed |
| WO-2023225324-A1 | METHODS AND COMPOSITIONS FOR TREATING FATTY LIVER AND VIRAL INFECTIONS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-11-23 | — | — | WO | disclosed |
| US-20120232062-A1 | AZAINDAZOLES TO TREAT FLAVIVIRIDAE VIRUS INFECTION | EIGER BIOPHARMACEUTICALS, INC. (US) | 2012-09-13 | — | — | US | disclosed |
| US-20120232062-A1 | AZAINDAZOLES TO TREAT FLAVIVIRIDAE VIRUS INFECTION | EIGER BIOPHARMACEUTICALS, INC. (US) | 2012-09-13 | — | — | US | disclosed |
| WO-2011049987-A2 | AZAINDAZOLES TO TREAT FLAVIVIRIDAE VIRUS INFECTION | EIGER BIOPHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232062-A1 | AZAINDAZOLES TO TREAT FLAVIVIRIDAE VIRUS INFECTION | HAVCR2, AZI2, ZC3HAV1 | PARP1 3673/4885ALDH1A1 564/4885POLB 3937/4885 |
| US-20250339444-A1 | Methods and Compositions for Treating Fatty Liver and Viral Infections | FABP1, FABP4, LIPC | PARP1 4100/4885ALDH1A1 3505/4885POLB 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.