SCHEMBL12174841

SCHEMBL12174841

Cc1cc(-c2cc(C)c(Br)s2)sc1Br

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757438 0.90 ESR2 (0.38) ESR1ESR2
SCHEMBL12737925 0.82 DAO (0.31)
SCHEMBL20764832 0.79 HSD17B1 (0.44) ESR1ESR2
SCHEMBL21300985 0.78
SCHEMBL3188614 0.77
SCHEMBL2183304 0.77
SCHEMBL2895252 0.76 CYP2A6 (0.34) ESR1ESR2
SCHEMBL15441215 0.76 CYP2A6 (0.45) ESR1ESR2
SCHEMBL14832601 0.76 KDM4E (0.33)
SCHEMBL9421386 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-10-03 US disclosed
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-10-03 US disclosed
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-10-03 US disclosed
US-20210047285-A1 Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION 2021-02-18 US disclosed
US-20210047285-A1 Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION 2021-02-18 US disclosed
US-10858334-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-12-08 US disclosed
US-10858334-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-12-08 US disclosed
EP-2270064-B1 Organic semiconductor polymer, transistor including an organic semiconductor polymer and methods of fabricating the same SAMSUNG ELECTRONICS CO LTD (KR) 2020-02-19 EP disclosed
US-20190210993-A1 Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-07-11 US disclosed
US-20190210993-A1 Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-07-11 US disclosed
US-9834640-B2 Nanoparticles CHROMITION LIMITED (GB) 2017-12-05 US disclosed
US-9831433-B2 Conjugated polymers and devices incorporating the same Raynergy Tek Incorporation (TW) 2017-11-28 US disclosed
US-20160141499-A1 CONJUGATED POLYMERS AND DEVICES INCORPORATING THE SAME Raynergy Tek Incorporation (TW) 2016-05-19 US disclosed
US-20140151680-A1 POLYMER COMPOUND AND ORGANIC TRANSISTOR USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-06-05 US disclosed
US-20110284082-A1 POLYMER CONTAINING THIOPHENE UNIT AND THIENYLENEVINYLENE UNIT, AND ORGANIC FIELD EFFECT TRANSISTOR AND ORGANIC SOLAR CELL CONTAINING THE POLYMER GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2011-11-24 US disclosed
US-7893190-B2 Alternating copolymers of phenylene vinylene and oligoarylene vinylene, preparation method thereof, and organic thin film transister comprising the same SAMSUNG ELECTRONICS CO., INC. (KR) 2011-02-22 US disclosed
US-20090120495-A1 Alternating copolymers of phenylene vinylene and oligoarylene vinylene, preparation method thereof, and organic thin flim transister comprising the same SAMSUNG ELECTRONICS CO., LTD. 2009-05-14 US disclosed
US-7470377-B2 Monomers, oligomers and polymers comprising thiophene and selenophene MERCK PATENT GMBH (DE) 2008-12-30 US disclosed
US-20080303000-A1 Monomers, Oligomers and Polymers Comprising Thiophene and Selenophene MERCK PATENT GMBH (DE) 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10858334-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst PPOX, TST, COX6C ESR1 2454/4885ESR2 2899/4885
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst PPOX, TST, COX6C ESR1 2454/4885ESR2 2899/4885
US-20190210993-A1 Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst PPOX, TST, COX6C ESR1 2454/4885ESR2 2899/4885
US-20080303000-A1 Monomers, Oligomers and Polymers Comprising Thiophene and Selenophene SELENOI, SELE, SLCO2A1 ESR1 668/4885ESR2 1346/4885
US-20210047285-A1 Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst PPOX, TST, COX6C ESR1 2454/4885ESR2 2899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.