Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12175382 | 0.85 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL823211 | 0.82 | MEN1 (0.43) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL823210 | 0.82 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL12104731 | 0.76 | NPC1 (0.47) | PDE4APDE4BPDE4CPDE4DRAB9A | |
| SCHEMBL823209 | 0.74 | MEN1 (0.49) | RAB9AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14214988 | 0.69 | MEN1 (0.53) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2736874 | 0.66 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL823207 | 0.66 | THRB (0.49) | RAB9AMEN1KMT2ACNR1CNR2 | |
| SCHEMBL12104600 | 0.66 | THRB (0.47) | RAB9AMEN1KMT2ACNR1CNR2 | |
| SCHEMBL15953037 | 0.66 | LIPG (0.55) | PDE4APDE4BPDE4CPDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137139-A1 | AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 2011-11-03 | — | — | WO | disclosed |