Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12175652 | 0.82 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DROCK2 | |
| SCHEMBL12175382 | 0.81 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DROCK2 | |
| SCHEMBL12104731 | 0.75 | NPC1 (0.47) | PDE4APDE4BPDE4CPDE4DROCK2 | |
| SCHEMBL823211 | 0.75 | MEN1 (0.43) | PDE4APDE4BPDE4CPDE4DROCK2 | |
| SCHEMBL823209 | 0.66 | MEN1 (0.49) | ALDH1A1SMN1; SMN2MYCMAPTMEN1 | |
| SCHEMBL823207 | 0.65 | THRB (0.49) | KDM4EALDH1A1CNR1MYCMAPT | |
| SCHEMBL12104600 | 0.65 | THRB (0.47) | KDM4EALDH1A1CNR1MYCMAPT | |
| SCHEMBL4536310 | 0.65 | CNR1 (0.62) | KDM4ENAMPTCNR1MAPTMEN1 | |
| SCHEMBL16352054 | 0.64 | NPC1 (0.59) | ALDH1A1SMN1; SMN2CNR1MYCMAPT | |
| SCHEMBL2212466 | 0.64 | NPC1 (0.59) | ALDH1A1SMN1; SMN2CNR1MYCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314265-B2 | Aromatic amic acids or amic esters and compositions | EASTMAN KODAK COMPANY (US) | 2012-11-20 | — | — | US | disclosed |
| US-20110269967-A1 | AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS | BANK OF AMERICA, N.A., AS AGENT | 2011-11-03 | — | — | US | disclosed |
| WO-2011137137-A1 | SEMICONDUCTING ARTICLES | EASTMAN KODAK COMPANY (US) | 2011-11-03 | — | — | WO | disclosed |
| US-20110266523-A1 | SEMICONDUCTING DEVICES AND METHODS OF PREPARING | BANK OF AMERICA, N.A., AS AGENT | 2011-11-03 | — | — | US | disclosed |
| US-20110269966-A1 | SEMICONDUCTING ARTICLES | CITICORP NORTH AMERICA, INC., AS AGENT | 2011-11-03 | — | — | US | disclosed |
| US-20110269265-A1 | METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES | KODAK REALTY INC. | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269966-A1 | SEMICONDUCTING ARTICLES | ALAD, PORCN, DDC | PDE4A 3338/4885PDE4B 3890/4885PDE4C 1850/4885 |
| US-20110269967-A1 | AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS | DDC, AADAC, MYOC | PDE4A 2984/4885PDE4B 3604/4885PDE4C 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.