Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGAV | P06756 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177518 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL12177123 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL12177542 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL12177442 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL12177449 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL12177415 | 0.73 | MGAM (0.52) | ALDH1A1POLBMAPTTDP1LMNA | |
| SCHEMBL14883357 | 0.72 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL12177138 | 0.71 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL12177159 | 0.71 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL12177126 | 0.70 | MGAM (0.54) | ALDH1A1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |