Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | MAX | P61244 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177456 | 0.87 | TDP1 (0.65) | ALDH1A1GAASMN1; SMN2PPARGMYC | |
| SCHEMBL12177715 | 0.85 | ALDH1A1 (0.53) | ALDH1A1GAASMN1; SMN2PPARGMYC | |
| SCHEMBL12177339 | 0.84 | PTPN1 (0.61) | ALDH1A1GAASMN1; SMN2AKR1B1MEN1 | |
| SCHEMBL12177201 | 0.81 | KMT2A (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL12177136 | 0.81 | CISD1 (0.56) | ALDH1A1GAASMN1; SMN2PPARGAKR1B1 | |
| SCHEMBL12177171 | 0.80 | PPARG (0.71) | ALDH1A1PPARGAKR1B1MEN1KMT2A | |
| SCHEMBL15828907 | 0.79 | CISD1 (0.72) | ALDH1A1PPARGMYCMAXNPC1 | |
| SCHEMBL6689181 | 0.79 | PPARG (0.70) | ALDH1A1PPARGAKR1B1MEN1KMT2A | |
| SCHEMBL6689183 | 0.79 | PPARG (0.70) | ALDH1A1PPARGAKR1B1MEN1KMT2A | |
| SCHEMBL12177341 | 0.78 | AKR1B1 (0.58) | ALDH1A1GAASMN1; SMN2PPARGAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |