Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | ACP1 | P24666 | 4/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177339 | 0.89 | PTPN1 (0.61) | AKR1B1ALDH1A1NLRP3GAASMN1; SMN2 | |
| SCHEMBL2586524 | 0.86 | ALDH1A1 (0.47) | AKR1B1ENPP2ALDH1A1NLRP3GAA | |
| SCHEMBL12177581 | 0.83 | ALDH1A1 (0.58) | AKR1B1PPARGALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12177496 | 0.82 | MEN1 (0.69) | ENPP2ALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL12177280 | 0.81 | NPC1 (0.66) | AKR1B1NLRP3PKMNPC1CASP3 | |
| SCHEMBL12177136 | 0.81 | CISD1 (0.56) | AKR1B1PPARGALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12177553 | 0.79 | PPARG (0.54) | AKR1B1PPARGALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12177132 | 0.78 | ALDH1A1 (0.50) | AKR1B1ENPP2ALDH1A1NLRP3GAA | |
| SCHEMBL12177456 | 0.78 | TDP1 (0.65) | AKR1B1PPARGALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12177156 | 0.78 | ALDH1A1 (0.61) | AKR1B1PPARGALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |