Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.63 |
| ▸ | ACP1 | P24666 | 4/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.61 |
| ▸ | ITGAV | P06756 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177731 | 0.91 | PTPN2 (0.61) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177501 | 0.91 | PTPN2 (0.61) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177682 | 0.89 | CA9 (0.70) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177442 | 0.88 | ALDH1A1 (0.62) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177530 | 0.86 | ALDH1A1 (0.59) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177391 | 0.84 | PTPN2 (0.57) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL31321765 | 0.82 | PTPN1 (0.66) | CA9PTPN2PTPN1ACP1ALDH1A1 | |
| SCHEMBL12177573 | 0.80 | AURKA (0.60) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177369 | 0.80 | LMNA (0.62) | ALDH1A1POLBMAPTTDP1MEN1 | |
| SCHEMBL12177688 | 0.80 | CA9 (0.57) | MGAMCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |