Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.56 |
| ▸ | CA1 | P00915 | 7/20 | 0.56 |
| ▸ | CA9 | Q16790 | 7/20 | 0.56 |
| ▸ | CA6 | P23280 | 5/20 | 0.56 |
| ▸ | CA7 | P43166 | 5/20 | 0.56 |
| ▸ | CA5A | P35218 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.56 |
| ▸ | CA4 | P22748 | 4/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356372 | 1.00 | CA2 (0.56) | CA2CA1CA9CA6CA7 | |
| Hydrochloric Acid SCHEMBL27864427 | 0.98 | CA2 (0.54) | CA2CA1CA9CA6CA7 | |
| SCHEMBL2323386 | 0.98 | CA2 (0.54) | CA2CA1CA9CA6CA7 | |
| SCHEMBL2323381 | 0.98 | CA2 (0.54) | CA2CA1CA9CA6CA7 | |
| SCHEMBL29578190 | 0.81 | PTGES2 (0.64) | CA2CA1CA9CA6CA7 | |
| SCHEMBL742940 | 0.81 | PTGES2 (0.64) | CA2CA1CA9CA6CA7 | |
| SCHEMBL11647231 | 0.81 | CA1 (0.52) | CA2CA1CA9CA6CA7 | |
| SCHEMBL202947 | 0.81 | CA2 (0.70) | CA2CA1CA9CA6CA7 | |
| SCHEMBL28407818 | 0.81 | CA2 (0.47) | CA2CA1CA9CA6CA7 | |
| SCHEMBL30697126 | 0.79 | HSD11B1 (0.59) | GAATSHRHSD17B10LMNAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2090 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479818-B2 | Treatment of fibrosis with IRE1 small molecule inhibitors | CORNELL UNIVERSITY (US) | 2025-11-25 | — | — | US | claimed |
| EP-3707126-B1 | IRE1 SMALL MOLECULE INHIBITORS | UNIV CORNELL (US) | 2025-05-14 | — | — | EP | claimed |
| CN-117643584-A | Preparation method of sulfachromone compound for candida albicans resistant medicine | 广西民族大学 | 2024-03-05 | — | — | CN | claimed |
| CN-111566089-B | IRE1 small molecule inhibitors | 康奈尔大学 | 2023-11-17 | — | — | CN | claimed |
| CN-111526877-B | Compounds and compositions for IRE1 inhibition | 奥普提卡拉公司 | 2023-08-25 | — | — | CN | claimed |
| CN-114432903-B | Composite membrane with acid resistance and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-114601752-A | Human-like collagen dressing with composite components | 上海医妃医药科技有限公司 | 2022-06-10 | — | — | CN | claimed |
| US-20220153734-A1 | Pyrazolopyridine Compounds For IRE1 Inhibition | Optikira, LLC | 2022-05-19 | — | — | US | claimed |
| CN-113634213-A | Preparation process of sulfonyl isocyanate with high conversion rate | 安徽广信农化股份有限公司 | 2021-11-12 | — | — | CN | claimed |
| EP-3891130-A1 | IRE1 SMALL MOLECULE INHIBITORS | Cornell University (US) | 2021-10-13 | — | — | EP | claimed |
| WO-1999050303-A2 | IMMUNE RESPONSE MODULATOR ALPHA-2 MACROGLOBULIN COMPLEX | DUKE UNIVERSITY (US) | 1999-10-07 | — | — | WO | claimed |
| CN-1171197-A | Method for synthesizing herbicide of sulfonylureas | ZHANG HUIMING (CN) | 1998-01-28 | — | — | CN | claimed |
| EP-0450487-A1 | Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | claimed |
| US-5034534-A | Catalytic carbonylation of aryl halides with palladium catalyst and phosphine ligands, cyclization to form saccharin | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-23 | — | — | US | claimed |
| US-4996284-A | Heating a sulfonamide and epoxy resin in the presence of a Lewis Acid | EMPAK, INC. | 1991-02-26 | — | — | US | claimed |
| WO-1990013609-A1 | NOVEL FLUORESCENT PIGMENT COMPOSITIONS AND A PROCESS FOR THEIR PREPARATION AND USE OF SAME | MALLAVARAPU LEO X (US) | 1990-11-15 | — | — | WO | claimed |
| WO-1990012829-A1 | NOVEL EPOXY SULFONAMIDE-BASED RESINS, A PROCESS FOR THEIR PREPARATION AND USE OF SAME | MALLAVARAPU LEO X (US) | 1990-11-01 | — | — | WO | claimed |
| EP-0132230-B1 | PROCESS FOR THE PREPARATION OF SULFONYL UREA | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | claimed |
| CN-85104674-A | Composition of benzenesulfonyl urea derivative and beta-cyclodextrin and preparation method thereof | — | 1986-12-24 | — | — | CN | claimed |
| EP-0132230-A2 | Process for the preparation of sulfonyl urea | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | claimed |