Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Malonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL20142282 | 0.96 | CA4 (0.83) | — | |
| Malonic Acid SCHEMBL15270467 | 0.96 | — | — | |
| Malonic Acid SCHEMBL19714757 | 0.91 | CA4 (0.91) | — | |
| Malonic Acid SCHEMBL5142880 | 0.91 | CA4 (0.91) | — | |
| Malonic Acid SCHEMBL2475920 | 0.91 | CA4 (0.91) | — | |
| Malonic Acid SCHEMBL9184127 | 0.91 | — | — | |
| Malonic Acid SCHEMBL21815638 | 0.91 | CA4 (0.91) | — | |
| Malonic Acid SCHEMBL21878522 | 0.91 | CA4 (0.91) | — | |
| Malonic Acid SCHEMBL21815790 | 0.91 | CA4 (0.91) | — | |
| Malonic Acid SCHEMBL21878520 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 588 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260069910-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE INHIBITING BIOCHEMICAL SOLUTIONS AND METHODS OF AND APPARATUS FOR APPLYING THE SAME TO PROTECT PROPERTY AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2026-03-12 | — | — | US | claimed |
| US-20260069911-A1 | ENVIRONMENTALLY-CLEAN FIRE INHIBITING BIOCHEMICAL COMPOSITIONS, SOLUTIONS AND POWDERS, AND METHODS OF AND APPARATUS FOR PRODUCING FIRE PROTECTED WOOD PRODUCTS | MIGHTY FIRE BREAKER LLC (US) | 2026-03-12 | — | — | US | claimed |
| US-20260048289-A1 | ENVIRONMENTALLY-SAFE WATER-BASED FIRE RETARDANT BIOCHEMICAL COMPOSITIONS FORMULATED USING ALKALI METAL SALTS, FREE FROM PHOSPHATES, NITRATES, AND AMMONIUM-SALTS, FOR NON-CORROSIVE AERIAL AND GROUND DELIVERY ONTO PROPERTY REQUIRING LONG-TERM PROTECTION AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2026-02-19 | — | — | US | claimed |
| EP-4072522-B1 | MALONATE SALT FOR USE IN THE TREATMENT OR PREVENTION OF ISCHAEMIC STROKE REPERFUSION INJURY | CAMBRIDGE ENTPR LTD (GB) | 2026-01-28 | — | — | EP | claimed |
| US-20260014403-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE INHIBITING BIOCHEMICAL COMPOSITIONS, SOLUTIONS, POWDERS AND METHODS OF AND APPARATUS FOR PRODUCING FIRE PROTECTED WOOD AND ENGINEERED WOOD PRODUCTS | MIGHTY FIRE BREAKER LLC (US) | 2026-01-15 | — | — | US | claimed |
| WO-2025245031-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE-INHIBITING BIOCHEMICAL SOLUTIONS, METHODS, AND APPARATUS FOR APPLYING TO PROTECT PROPERTY AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2025-11-27 | — | — | WO | claimed |
| US-20250128108-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE INHIBITING BIOCHEMICAL SOLUTIONS FORMULATED USING ALKALI METAL SALTS OF MALONIC ACID FOR PROTECTING PROPERTY AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2025-04-24 | — | — | US | claimed |
| US-20240366982-A1 | ENVIRONMENTALLY-CLEAN WATER-BASED FIRE INHIBITING BIOCHEMICAL COMPOSITIONS AND METHODS OF AND APPARATUS FOR APPLYING THE SAME TO PROTECT PROPERTY AGAINST WILDFIRE | MIGHTY FIRE BREAKER LLC (US) | 2024-11-07 | — | — | US | claimed |
| CN-118218377-A | Dry-method cooperative fixation and product recycling treatment method for municipal solid waste incineration fly ash chloride ions and heavy metals | 江苏理工学院 | 2024-06-21 | — | — | CN | claimed |
| US-11850294-B2 | Buffered microencapsulated compositions and methods | PREMIER DENTAL PRODUCTS COMPANY (US) | 2023-12-26 | — | — | US | claimed |
| EP-1112178-A1 | METHOD FOR TREATING CALCIUM BORATE ORES TO OBTAIN USEFUL BORON COMPOUNDS | Specialty Boron Products, Llc (US) | 2001-07-04 | — | — | EP | claimed |
| US-6159449-A | Dentifrice products and methods for remineralizing and/or mineralizing teeth | ENAMELON, INC. (US) | 2000-12-12 | — | — | US | claimed |
| WO-2000047173-A1 | REMINERALIZING/MINERALIZING ORAL PRODUCTS HAVING IMPROVED WHITENING AND STAIN REMOVAL PROPERTIES | ENAMELON, INC. (US) | 2000-08-17 | — | — | WO | claimed |
| WO-2000009326-A1 | METHOD FOR TREATING CALCIUM BORATE ORES TO OBTAIN USEFUL BORON COMPOUNDS | SPECIALTY BORON PRODUCTS, LLC (US) | 2000-02-24 | — | — | WO | claimed |
| EP-0930867-A1 | IMPROVED PRODUCTS AND METHODS FOR THE REMINERALIZATION AND PREVENTION OF DEMINERALIZATION OF TEETH | Enamelon, Inc. (US) | 1999-07-28 | — | — | EP | claimed |
| WO-1998043602-A1 | DENTIFRICE PRODUCTS AND METHODS FOR REMINERALIZING AND/OR MINERALIZING TEETH | ENAMELON, INC. (US) | 1998-10-08 | — | — | WO | claimed |
| WO-1998013013-A1 | IMPROVED PRODUCTS AND METHODS FOR THE REMINERALIZATION AND PREVENTION OF DEMINERALIZATION OF TEETH | ENAMELON, INC. (US) | 1998-04-02 | — | — | WO | claimed |
| WO-1998013012-A1 | IMPROVED PRODUCTS AND METHODS FOR THE REMINERALIZATION AND PREVENTION OF DEMINERALIZATION OF TEETH | ENAMELON, INC. (US) | 1998-04-02 | — | — | WO | claimed |
| US-5281265-A | Calcium sulfate, calcium succinate, calcium malate, calcium malonate, calcium maleate, and setting component comprising water soluble carboxylic acid salts, phosphate salts | CERAMEDICAL, INC. | 1994-01-25 | — | — | US | claimed |
| US-3989500-A | WITH THIOUREA DERIVATIVES | ALLIED CHEMICAL CORPORATION (US) | 1976-11-02 | — | — | US | claimed |