Methacrylic Acid

Methacrylic Acid

SCHEMBL1218950

C=C(C)C(=O)O.CCCl.CN(C)C

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 4/20 0.32
ALDH1A1 P00352 3/20 0.32
FFAR3 O14843 2/20 0.32
THRB P10828 1/20 0.31
TGFBR1 P36897 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL16506807 0.89 TDP1 (0.40) TDP1HSD17B10TSHRALDH1A1FFAR3
Methacrylic Acid SCHEMBL9681885 0.86 TDP1 (0.40) TDP1HSD17B10TSHRALDH1A1FFAR3
Methacrylic Acid SCHEMBL28229822 0.86 TDP1 (0.44) TDP1HSD17B10TSHRALDH1A1FFAR3
Methacrylic Acid SCHEMBL284735 0.86 TDP1 (0.44) TDP1HSD17B10TSHRALDH1A1FFAR3
Methacrylic Acid SCHEMBL27743356 0.84 TDP1 (0.41) TDP1TSHRALDH1A1FFAR3THRB
Methacrylic Acid SCHEMBL15917025 0.83 TDP1 (0.42) TDP1HSD17B10TSHRALDH1A1FFAR3
Methacrylic Acid SCHEMBL1071243 0.83 TDP1 (0.42) TDP1HSD17B10TSHRALDH1A1FFAR3
Methacrylic Acid SCHEMBL28096441 0.83
Methacrylic Acid SCHEMBL1071245 0.83 TDP1 (0.42) TDP1HSD17B10TSHRALDH1A1FFAR3
Methacrylic Acid SCHEMBL7596069 0.83 TDP1 (0.42) TDP1HSD17B10TSHRALDH1A1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063351-A Green synthesis of chiral beta amino acids using biological enzymes and immobilized aminotransferase used 北京元延医药科技股份有限公司 2024-05-24 CN claimed
US-4828840-A Sustained-release formulation and production thereof SHIONOGI & CO., LTD. (JP) 1989-05-09 US claimed
CN-113194950-B Treatment and prevention of premature ejaculation (PE) 塞罗亚克PME贸易有限公司 2024-10-11 CN disclosed
US-11738064-B2 Pharmaceutical composition for preventing and treating eye diseases, containing as active ingredient, fusion protein in which tissue-penetrating peptide and anti-vascular endothelial growth factor preparation are fused ILDONG PHARM CO., LTD. (KR) 2023-08-29 US disclosed
US-20230093570-A1 SOLID PREPARATION SCREEN Holdings Co., Ltd. (JP) 2023-03-23 US disclosed
CN-112451493-B Abuse-preventing oxycodone oral sustained-release tablet and preparation method thereof 江苏恩华药业股份有限公司 2022-06-28 CN disclosed
CN-112402386-B Abuse-preventing opioid oral sustained-release tablet and preparation method thereof 江苏恩华药业股份有限公司 2022-06-28 CN disclosed
EP-3973977-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING EYE DISEASES, CONTAINING, AS ACTIVE INGREDIENT, FUSION PROTEIN IN WHICH TISSUE-PENETRATING PEPTIDE AND ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR PREPARATION ARE FUSED Ildong Pharm Co., Ltd. (KR) 2022-03-30 EP disclosed
WO-2022029938-A1 SKIN COMPOSITION マルホ株式会社 2022-02-10 WO disclosed
CN-113194950-A Treatment and prevention of Premature Ejaculation (PE) 塞罗亚克PME贸易有限公司 2021-07-30 CN disclosed
CN-112451493-A Abuse-proof oxycodone oral sustained-release tablet and preparation method thereof 江苏恩华药业股份有限公司 2021-03-09 CN disclosed
US-7956211-B2 Trithiocarbonate derivatives and the use thereof in the form of transfer agents for acrylic acid controlled radical polymerisation COATEX S.A.S. (FR) 2011-06-07 US disclosed
US-20110033558-A1 POLYMERS PRODUCED BY USING SULPHUR COMPOUNDS IN THE FORM OF TRANSFER AGENTS FOR CONTROLLED RADICAL POLYMERISATION OF ACRYLIC ACID AND THE USE THEREOF COATEX S.A.S. (FR) 2011-02-10 US disclosed
US-7851572-B2 Polymers produced by using sulphur compounds in the form of transfer agents for controlled radical polymerisation of acrylic acid and the use thereof COATEX S.A.S. (FR) 2010-12-14 US disclosed
US-20070197747-A1 Polymers Produced By Using Sulphur Compounds In The Form Of Transfer Agents For Controlled Radical Polymerisation Of Acrylic Acid And The Use Thereof COATEX S.A.S. (FR) 2007-08-23 US disclosed
US-20070179262-A1 Trithiocarbonate derivatives and the use thereof in the form of transfer agents for acrylic acid controlled radical polymerisation COATEX S.A.S. (FR) 2007-08-02 US disclosed
EP-0807433-A1 SUSTAINED-RELEASE PREPARATION KANEBO LTD. (JP) 1997-11-19 EP disclosed
EP-0253684-B1 SUBSTAINED-RELEASE FORMULATION AND PRODUCTION THEREOF SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1991-04-10 EP disclosed
US-4828840-A Sustained-release formulation and production thereof SHIONOGI & CO., LTD. (JP) 1989-05-09 US disclosed
EP-0253684-A1 Substained-release formulation and production thereof SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1988-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110033558-A1 POLYMERS PRODUCED BY USING SULPHUR COMPOUNDS IN THE FORM OF TRANSFER AGENTS FOR CONTROLLED RADICAL POLYMERISATION OF ACRYLIC ACID AND THE USE THEREOF ASS1, HPRT1, GRHPR TDP1 2466/4885HSD17B10 1908/4885TSHR 4236/4885
US-20070179262-A1 Trithiocarbonate derivatives and the use thereof in the form of transfer agents for acrylic acid controlled radical polymerisation TST, AS3MT, TTPA TDP1 1486/4885HSD17B10 2130/4885TSHR 1032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.