Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12172762 | 0.85 | NR4A1 (0.71) | MAPTMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL10361953 | 0.83 | NR4A1 (0.73) | MAPTMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL1262239 | 0.81 | TGM2 (0.61) | MAPTMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL283513 | 0.77 | MMP1 (0.51) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL4950655 | 0.77 | MAPT (0.68) | MAPTMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL6587982 | 0.77 | NMT1 (0.70) | MAPTMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL3200856 | 0.77 | MAPT (0.67) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL26034043 | 0.77 | NMT1 (0.70) | MAPTMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL5175946 | 0.77 | MAPT (0.67) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL13675894 | 0.76 | TRPV1 (0.67) | MAPTMEN1KMT2ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120232150-A1 | PHTHALANILATE COMPOUNDS AND METHODS OF USE | University of Nortre Dame du Lac | 2012-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232150-A1 | PHTHALANILATE COMPOUNDS AND METHODS OF USE | MPO, ALPI, NQO1 | MAPT 2792/4885MEN1 2365/4885KMT2A 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.