Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TDP2 | O95551 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MMP1 | P03956 | 9/20 | 0.65 |
| ▸ | MMP2 | P08253 | 9/20 | 0.65 |
| ▸ | MMP9 | P14780 | 9/20 | 0.65 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MB | P02144 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175946 | 1.00 | MAPT (0.67) | MAPTTDP2GAATHRBL3MBTL1 | |
| SCHEMBL7771158 | 0.87 | MAPT (0.84) | MAPTTDP2GAATHRBL3MBTL1 | |
| SCHEMBL7771152 | 0.87 | MAPT (0.84) | MAPTTDP2GAATHRBL3MBTL1 | |
| SCHEMBL26034043 | 0.84 | NMT1 (0.70) | MAPTTHRBMMP1MMP2MMP9 | |
| SCHEMBL6587982 | 0.84 | NMT1 (0.70) | MAPTTHRBMMP1MMP2MMP9 | |
| SCHEMBL20280569 | 0.82 | TGM2 (0.67) | MAPTTDP2GAATHRBL3MBTL1 | |
| SCHEMBL31501449 | 0.82 | MAPT (0.55) | MAPTTDP2GAATHRBL3MBTL1 | |
| SCHEMBL29246294 | 0.82 | TGM2 (0.61) | MAPTL3MBTL1MMP1MMP2MMP9 | |
| SCHEMBL27947098 | 0.82 | MAPT (0.55) | MAPTTDP2GAATHRBL3MBTL1 | |
| SCHEMBL11835143 | 0.82 | MAPT (0.66) | MAPTGAATHRBL3MBTL1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058318-B1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | MITSUI CHEMICALS INC (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2058318-A1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2009-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | CAD, PPIP5K2, SLC20A1 | MAPT 86/4885TDP2 3926/4885GAA 3299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.