SCHEMBL1219243

SCHEMBL1219243

Fc1cccc(P(c2ccccc2)c2ccccc2)n1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
CYP3A4 P08684 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
DRD1 P21728 1/20 0.33
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
NFKB1 P19838 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2846416 0.84 TDP1 (0.55) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL9333180 0.82 KDM4E (0.58) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL9333200 0.82 KDM4E (0.58) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL1217644 0.75 GAA (0.45) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL231108 0.75 KDM4E (0.45) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL1219299 0.75 KDM4E (0.45) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL5843107 0.75 KDM4E (0.45) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL1217002 0.75 KDM4E (0.45) KDM4EGAACYP3A4TDP1ESR1
SCHEMBL8634770 0.75 KDM4E (0.41) KDM4EGAACYP3A4TDP1MAPT
SCHEMBL1219103 0.73 MEN1 (0.58) KDM4EGAACYP3A4TDP1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112175006-A Preparation method of pyridine diphenylphosphine derivative 河南省科学院化学研究所有限公司 2021-01-05 CN disclosed
EP-2256102-B1 PROCESS FOR PRODUCTION OF ALKOXYCARBONYL COMPOUND SUMITOMO CHEMICAL CO (JP) 2018-09-26 EP disclosed
US-9530974-B2 Copper complexes for optoelectronic applications CYNORA GMBH (DE) 2016-12-27 US disclosed
US-9530974-B2 Copper complexes for optoelectronic applications CYNORA GMBH (DE) 2016-12-27 US disclosed
EP-2828232-B1 PROCESS FOR PRODUCING ALKYL METHACRYLATE SUMITOMO CHEMICAL CO (JP) 2016-04-20 EP disclosed
US-20150194617-A1 COPPER COMPLEXES FOR OPTOELECTRONIC APPLICATIONS SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-09 US disclosed
US-20150194617-A1 COPPER COMPLEXES FOR OPTOELECTRONIC APPLICATIONS SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-09 US disclosed
US-9012639-B2 Copper complexes for optoelectronic applications CYNORA GMBH (DE) 2015-04-21 US disclosed
US-9012639-B2 Copper complexes for optoelectronic applications CYNORA GMBH (DE) 2015-04-21 US disclosed
EP-2828232-A1 PROCESS FOR PRODUCING ALKYL METHACRYLATE Sumitomo Chemical Company Limited (JP) 2015-01-28 EP disclosed
EP-2502927-B1 Copper complexes for optoelectronic applications CYNORA GMBH (DE) 2014-04-16 EP disclosed
WO-2013141004-A1 PROCESS FOR PRODUCING ALKYL METHACRYLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-09-26 WO disclosed
US-8399699-B2 Process for production of alkoxycarbonyl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-19 US disclosed
EP-2502927-A1 Copper complexes for optoelectronic applications Cynora GmbH (DE) 2012-09-26 EP disclosed
US-20120184738-A1 COPPER COMPLEXES FOR OPTOELECTRONIC APPLICATIONS CYNORA GMBH (DE) 2012-07-19 US disclosed
US-20120184738-A1 COPPER COMPLEXES FOR OPTOELECTRONIC APPLICATIONS CYNORA GMBH (DE) 2012-07-19 US disclosed
WO-2011111806-A1 METHOD FOR PRODUCING α, β-UNSATURATED CARBOXYLATE, AND CATALYST FOR PRODUCING THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-15 WO disclosed
US-20110046417-A1 PROCESS FOR PRODUCTION OF ALKOXYCARBONYL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-24 US disclosed
WO-2010149748-A1 COPPER COMPLEXES FOR OPTOELECTRONIC APPLICATIONS YERSIN HARTMUT (DE) 2010-12-29 WO disclosed
EP-2256102-A1 PROCESS FOR PRODUCTION OF ALKOXYCARBONYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046417-A1 PROCESS FOR PRODUCTION OF ALKOXYCARBONYL COMPOUND ADH1A, NAA50, NAA10 KDM4E 767/4885GAA 3320/4885CYP3A4 1204/4885
US-20120184738-A1 COPPER COMPLEXES FOR OPTOELECTRONIC APPLICATIONS AOC2, AOC3, OCIAD2 KDM4E 3110/4885GAA 4535/4885CYP3A4 2864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.