Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.86 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.80 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.80 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.80 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.80 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.80 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.80 |
| ▸ | CES2 | O00748 | 1/20 | 0.80 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.80 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.80 |
| ▸ | FAAH | O00519 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.68 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.68 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.68 |
| ▸ | PRKCA | P17252 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848249 | 1.00 | DGKA (0.86) | DGKALPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL5944443 | 1.00 | DGKA (0.86) | DGKALPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL2733309 | 1.00 | DGKA (0.86) | DGKALPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL11782255 | 1.00 | DGKA (0.86) | DGKALPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL18197507 | 1.00 | DGKA (0.86) | DGKALPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL1219747 | 1.00 | DGKA (0.86) | DGKALPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL17099733 | 1.00 | DGKA (0.86) | DGKALPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL5944442 | 1.00 | DGKA (0.86) | DGKALPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL16083710 | 1.00 | DGKA (0.86) | DGKALPAR1LPAR4LPAR2LPAR3 | |
| SCHEMBL11429486 | 1.00 | DGKA (0.86) | DGKALPAR1LPAR4LPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012122144-A1 | HIGHLY MONODISPERSE BRANCHED PEG-LIPID CONJUGATES | WU NIAN (US) | 2012-09-13 | — | — | WO | disclosed |
| US-20120232169-A1 | HIGHLY MONODISPERSE BRANCHED PEG-LIPID CONJUGATES | BIOZONE PHARMACEUTICALS, INC. (US) | 2012-09-13 | — | — | US | disclosed |
| EP-2437756-A2 | PURE PEG-LIPID CONJUGATES | Wu, Nian (US) | 2012-04-11 | — | — | EP | disclosed |
| US-20110040113-A1 | Pure PEG-lipid conjugates | WU NIAN | 2011-02-17 | — | — | US | disclosed |
| WO-2010141069-A2 | PURE PEG-LIPID CONJUGATES | WU NIAN (US) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232169-A1 | HIGHLY MONODISPERSE BRANCHED PEG-LIPID CONJUGATES | LIPA, CETP, DGAT2 | DGKA 30/4885LPAR1 513/4885LPAR4 360/4885 |
| US-20110040113-A1 | Pure PEG-lipid conjugates | DGAT2, MGLL, DGAT1 | DGKA 65/4885LPAR1 241/4885LPAR4 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.