Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839293 | 0.87 | RAB9A (0.81) | RAB9AHTTTSHRSMN1; SMN2MEN1 | |
| SCHEMBL8887757 | 0.83 | RAB9A (0.75) | RAB9AHTTTSHRSMN1; SMN2MEN1 | |
| SCHEMBL2840873 | 0.81 | TSHR (0.74) | RAB9ATSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1104176 | 0.81 | RAB9A (0.76) | RAB9AHTTTSHRSMN1; SMN2MEN1 | |
| SCHEMBL31323285 | 0.81 | RAB9A (0.71) | RAB9AHTTTSHRSMN1; SMN2MEN1 | |
| SCHEMBL9422337 | 0.79 | SMN1; SMN2 (0.73) | RAB9ATSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12199548 | 0.79 | RAB9A (0.57) | RAB9ATSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2157944 | 0.78 | RAB9A (0.59) | RAB9ATSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10941324 | 0.78 | NAMPT (0.69) | RAB9ATSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5879030 | 0.78 | RAB9A (0.88) | RAB9AHTTTSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9408919-B2 | Biodegradable polymer—bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2016-08-09 | — | — | US | disclosed |
| US-9408919-B2 | Biodegradable polymer—bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2016-08-09 | — | — | US | disclosed |
| US-20140046018-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | POLYACTIVA PTY LTD. (AU) | 2014-02-13 | — | — | US | disclosed |
| US-20140046018-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | POLYACTIVA PTY LTD. (AU) | 2014-02-13 | — | — | US | disclosed |
| US-8535655-B2 | Biodegradable polymer—bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2013-09-17 | — | — | US | disclosed |
| US-8535655-B2 | Biodegradable polymer—bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2013-09-17 | — | — | US | disclosed |
| US-20110243884-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | THE BIONICS INSTITUTE OF AUSTRALIA (AU) | 2011-10-06 | — | — | US | disclosed |
| US-20110243884-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | THE BIONICS INSTITUTE OF AUSTRALIA (AU) | 2011-10-06 | — | — | US | disclosed |
| WO-2010040187-A1 | POLYMER-BIOACTIVE AGENT CONJUGATES | THE BIONIC EAR INSTITUTE (AU) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046018-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | BMP2, MKI67, FGF2 | RAB9A 1738/4885HTT 3407/4885TSHR 3674/4885 |
| US-20110243884-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | BMP2, MKI67, FGF2 | RAB9A 1738/4885HTT 3407/4885TSHR 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.