Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199536 | 0.87 | RAB9A (0.69) | RAB9ASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL8887757 | 0.84 | RAB9A (0.75) | RAB9ASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL2840873 | 0.83 | TSHR (0.74) | RAB9ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL10627841 | 0.82 | RAB9A (0.71) | RAB9ASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL31323285 | 0.82 | RAB9A (0.71) | RAB9ASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL1104176 | 0.82 | RAB9A (0.76) | RAB9ASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL8839398 | 0.80 | RAB9A (0.57) | RAB9ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL9422337 | 0.80 | SMN1; SMN2 (0.73) | RAB9ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL2157944 | 0.79 | RAB9A (0.59) | RAB9ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL4289783 | 0.79 | HPGD (0.71) | RAB9ASMN1; SMN2ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650428-A | THROMBOXANE A2 ANTAGONISM | NKK CORPORATION (JP) | 1997-07-22 | — | — | US | disclosed |