Drinidene

Drinidene

SCHEMBL121997

N/C=C1\Cc2ccccc2C1=O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.65
MIF P14174 5/20 0.62
MAOB P27338 2/20 0.62
KDM4E B2RXH2 4/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
CYP19A1 P11511 2/20 0.60
TNF P01375 2/20 0.60
MAPT P10636 5/20 0.58
CES1 P23141 2/20 0.55
BCHE P06276 1/20 0.55
ALDH1A1 P00352 4/20 0.54
POLB P06746 2/20 0.54
HPGD P15428 2/20 0.54
GAA P10253 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ACHE P22303 1/20 0.51
STK17B O94768 1/20 0.51
RAB9A P51151 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Drinidene SCHEMBL2188657 1.00 MAOA (0.65) MAOAMIFMAOBKDM4EMEN1
Drinidene SCHEMBL2188660 1.00 MAOA (0.65) MAOAMIFMAOBKDM4EMEN1
Drinidene SCHEMBL28279862 0.96 CYP19A1 (0.61) MAOAMIFMAOBKDM4EMEN1
SCHEMBL2319027 0.85 MAOA (0.90) MAOAMIFMAOBKDM4EMEN1
SCHEMBL10673520 0.83 MAOA (0.50) MAOAMIFMAOBKDM4EMEN1
Anthrone SCHEMBL28117197 0.81 MAOA (0.90) MAOAMIFMAOBKDM4EMEN1
Anthrone SCHEMBL29448801 0.80 MAOA (1.00) MAOAMIFMAOBKDM4EMEN1
Anthrone SCHEMBL1527782 0.80 MAOA (1.00) MAOAMIFMAOBKDM4EMEN1
Anthrone SCHEMBL29357010 0.80 MAOA (1.00) MAOAMIFMAOBKDM4EMEN1
Anthrone SCHEMBL18143 0.80 MAOA (1.00) MAOAMIFMAOBKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-4719353-A1 REVERSIBLE SURFACTANT AND MULTIFUNCTIONAL DRUG DELIVERY SYSTEMS BASED THEREON Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2026-04-08 EP disclosed
WO-2025109604-A1 DOLASTATIN 10 ANALOGS Ariel Scientific Innovations Ltd. (IL) 2025-05-30 WO disclosed
US-20250152319-A1 ORAL APPLIANCE FOR DELIVERY OF MEDICAMENTS AND/OR OTHER SUBSTANCES Emanate Biomedical, Inc. (US) 2025-05-15 US disclosed
US-12296085-B2 Method for extracorporeal treatment of preeclampsia and related disorders ImMutriX Therapeutics, Inc. (US) 2025-05-13 US disclosed
US-20250049928-A1 ANESTHETIC PRODRUGS AND DERIVATIVES THEREOF FOR PROLONGED SENSORY SELECTIVE NERVE BLOCKAGE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA 2025-02-13 US disclosed
EP-4051691-B1 DOLASTATIN 10 ANALOG ARIEL SCIENT INNOVATIONS LTD (IL) 2025-02-12 EP disclosed
US-20250032221-A1 ORTHODONTIC DEVICES FOR DELIVERY OF AN ACTIVE AGENT Smylio Inc. (US) 2025-01-30 US disclosed
US-12207984-B2 Oral appliance for delivery of medicaments and/or other substances Emanate Biomedical, Inc. (US) 2025-01-28 US disclosed
EP-3689357-B1 COMPOSITIONS FOR CELLULAR RESTORATION AND METHODS OF MAKING AND USING SAME ADVANCED REGEN MEDICAL TECH LLC (US) 2024-12-04 EP disclosed
WO-2001007009-A1 LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed
WO-2001006829-A2 LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed
EP-1054998-A1 TRANSGLUTAMINASE LINKAGE OF AGENTS TO TISSUE Pericor Science, Inc. (US) 2000-11-29 EP disclosed
WO-2000050020-A2 USE OF SULFAMATE DERIVATIVES FOR TREATING IMPULSE CONTROL DISORDERS UNIVERSITY OF CINCINNATI (US) 2000-08-31 WO disclosed
WO-2000040604-A2 METHODS AND COMPOSITIONS FOR MODULATING CYTOKINE RELEASE BY αEβ7-EXPRESSING CELLS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2000-07-13 WO disclosed
WO-1999036570-A2 TRANSGLUTAMINASE LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE INC (US) 1999-07-22 WO disclosed
WO-1999030690-A1 ORAL DELIVERY FORMULATION AXIA THERAPEUTICS, INC. (US) 1999-06-24 WO disclosed
EP-0909183-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES Neuromedica, Inc. (US) 1999-04-21 EP disclosed
US-5795909-A ANTICARCINOGENIC AND ANTITUMOR AGENTS; BREAST, COLON, OVARIANCANCERS NEUROMEDICA, INC. (US) 1998-08-18 US disclosed
WO-1997044063-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES NEUROMEDICA, INC. (US) 1997-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049928-A1 ANESTHETIC PRODRUGS AND DERIVATIVES THEREOF FOR PROLONGED SENSORY SELECTIVE NERVE BLOCKAGE TRPV1, OPRL1, TRPA1 MAOA 1291/4885MIF 4207/4885MAOB 394/4885
US-12296085-B2 Method for extracorporeal treatment of preeclampsia and related disorders TEK, FLT4, PGF MAOA 4803/4885MIF 1215/4885MAOB 4776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.