Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124807 | 0.77 | TLR7 (0.55) | TLR7CA1CA2CA9CA12 | |
| SCHEMBL24076836 | 0.77 | MEN1 (0.55) | TLR7CA1CA2CA9CA12 | |
| SCHEMBL24076838 | 0.75 | MEN1 (0.54) | TLR7CA1CA2CA9CA12 | |
| Piperazine SCHEMBL1317991 | 0.74 | MEN1 (0.55) | TLR7MEN1USP2POLBPPARG | |
| SCHEMBL16124815 | 0.72 | TLR7 (0.50) | TLR7CA1CA2CA9CA12 | |
| SCHEMBL12119403 | 0.72 | TGM2 (0.61) | TLR7MEN1USP2POLBPPARG | |
| SCHEMBL16253380 | 0.72 | MEN1 (0.60) | TLR7CA1CA2CA9CA12 | |
| SCHEMBL11964672 | 0.72 | MEN1 (0.60) | TLR7CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL13737398 | 0.71 | TGM2 (0.60) | TLR7MEN1USP2POLBPPARG | |
| SCHEMBL13815111 | 0.71 | MEN1 (0.57) | TLR7CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034800-B2 | Cross-bridged tetraamine macrocycles complexed with transition metal ions, radioactive metal species, fluorescent tag; as CXCR4 co-receptor antagonist is a dosage form for treatment of HIV; radiopharmaceutical for imaging chemokine receptors; drug screening assays for chemokine receptor binding | UNIVERSITY OF HULL (GB) | 2011-10-11 | — | — | US | disclosed |
| US-20080267866-A1 | Novel Antiviral Macrocycle Derivatives and Metal Complexes, Incorporating Bridged Macrocycles | UNIVERSITY OF HULL (GB) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267866-A1 | Novel Antiviral Macrocycle Derivatives and Metal Complexes, Incorporating Bridged Macrocycles | ZC3HAV1, ZC3HAV1L, GAR1 | TLR7 1247/4885CA1 1565/4885CA2 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.