SCHEMBL12203264

SCHEMBL12203264

CNC(=O)NCCCN1C(=O)C=CC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 5/20 0.50
▸ OPRM1 P35372 4/20 0.50
▸ OPRD1 P41143 4/20 0.50
▸ OPRK1 P41145 4/20 0.50
▸ FAAH O00519 3/20 0.50
▸ HSP90AA1 P07900 1/20 0.48
▸ TLR9 Q9NR96 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ TP53 P04637 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ PKM P14618 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ XBP1 P17861 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ RECQL P46063 1/20 0.48
▸ RAB9A P51151 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13865204 0.89 OPRM1 (0.43) MGLLOPRM1OPRD1OPRK1FAAH
SCHEMBL17740045 0.85 PTGS1 (0.53) MGLLOPRM1OPRD1OPRK1FAAH
SCHEMBL19703580 0.83 MGLL (0.61) MGLLOPRM1OPRD1OPRK1FAAH
SCHEMBL19698122 0.81 OPRM1 (0.49) MGLLOPRM1OPRD1OPRK1FAAH
SCHEMBL3794652 0.80 MGLL (0.56) MGLLOPRM1OPRD1OPRK1FAAH
SCHEMBL3270615 0.80 MGLL (0.56) MGLLOPRM1OPRD1OPRK1FAAH
SCHEMBL19704564 0.80 PTGS1 (0.56) MGLLOPRM1OPRD1OPRK1FAAH
SCHEMBL19703879 0.80 PTGS1 (0.66) MGLLOPRM1OPRD1OPRK1FAAH
SCHEMBL19698144 0.80 OPRM1 (0.48) MGLLOPRM1OPRD1OPRK1FAAH
SCHEMBL13310414 0.79 MGLL (0.50) MGLLOPRM1OPRD1OPRK1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10890532-B2 Compositions and methods for performing assays PALO ALTO RESEARCH CENTER INCORPORATED (US) 2021-01-12 — — US disclosed
US-8034928-B2 Fluorescence assays with improved sensitivity WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-10-11 — — US disclosed
US-8034928-B2 Fluorescence assays with improved sensitivity WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-10-11 — — US disclosed
US-20090299061-A1 FLUORESCENCE ASSAYS WITH IMPROVED SENSITIVITY PENN STATE RESEARCH FOUNDATION 2009-12-03 — — US disclosed
US-20090299061-A1 FLUORESCENCE ASSAYS WITH IMPROVED SENSITIVITY PENN STATE RESEARCH FOUNDATION 2009-12-03 — — US disclosed
US-7534902-B2 Fluorescence assays with improved sensitivity WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-05-19 — — US disclosed
US-7534902-B2 Fluorescence assays with improved sensitivity WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299061-A1 FLUORESCENCE ASSAYS WITH IMPROVED SENSITIVITY UACA, HNRNPUL1, FUS MGLL 2129/4885OPRM1 2903/4885OPRD1 4362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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