Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.56 |
| ▸ | FAAH | O00519 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021061 | 0.93 | MGLL (0.61) | MGLLFAAHPTGS1PTGS2HSP90AA1 | |
| SCHEMBL16095854 | 0.93 | MGLL (0.61) | MGLLFAAHPTGS1PTGS2HSP90AA1 | |
| SCHEMBL18919435 | 0.90 | PTGS1 (0.49) | MGLLFAAHPTGS1PTGS2HSP90AA1 | |
| SCHEMBL16096215 | 0.88 | PTGS1 (0.48) | MGLLFAAHPTGS1PTGS2HSP90AA1 | |
| SCHEMBL3270615 | 0.85 | MGLL (0.56) | MGLLFAAHPTGS1PTGS2HSP90AA1 | |
| SCHEMBL17841910 | 0.82 | PTGS1 (0.61) | MGLLFAAHPTGS1PTGS2HSP90AA1 | |
| SCHEMBL12203264 | 0.80 | MGLL (0.50) | MGLLFAAHPTGS1PTGS2HSP90AA1 | |
| SCHEMBL20575000 | 0.80 | PTGS1 (0.46) | MGLLFAAHPTGS1PTGS2HSP90AA1 | |
| SCHEMBL13310414 | 0.80 | MGLL (0.50) | MGLLFAAHPTGS1PTGS2HSP90AA1 | |
| SCHEMBL29444954 | 0.80 | NPC1 (0.55) | MGLLFAAHALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024116053-A1 | PCTA DERIVATIVES, CONJUGATES THEREOF AND USES THEREOF | NOVARTIS AG (CH) | 2024-06-06 | — | — | WO | disclosed |
| US-20220054658-A1 | CONJUGATES | TRANSFECTION HOLDINGS LIMITED (NZ) | 2022-02-24 | — | — | US | disclosed |
| EP-3897737-A1 | CONJUGATES | Transfection Holdings Limited (NZ) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020127602-A1 | CONJUGATES | TRANSFECTION HOLDINGS LIMITED (NZ) | 2020-06-25 | — | — | WO | disclosed |
| US-20100297025-A1 | Novel compositions magnetic particles covered with gem-bisphosphonate derivatives | GUERBET. | 2010-11-25 | — | — | US | disclosed |
| US-7780953-B2 | Compositions magnetic particles covered with gem-bisphosphonate derivatives | GUERBET (FR) | 2010-08-24 | — | — | US | disclosed |
| EP-1572246-B1 | NOVEL COMPOSITIONS OF MAGNETIC PARTICLES COVERED WITH GEM-BISPHOSPHONATE DERIVATIVES | GUERBET SA (FR) | 2009-02-25 | — | — | EP | disclosed |
| US-20040253181-A1 | Novel compositions magnetic particles covered with gem-bisphosphonate derivatives | GUERBET (FR) | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297025-A1 | Novel compositions magnetic particles covered with gem-bisphosphonate derivatives | PHOSPHO1, SGMS2, PTEN | MGLL 663/4885FAAH 675/4885PTGS1 1492/4885 |
| US-20220054658-A1 | CONJUGATES | RTN3, RER1, HRH4 | MGLL 2455/4885FAAH 1195/4885PTGS1 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.