Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785998 | 0.84 | ALDH1A1 (0.50) | ALOX15CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL31238899 | 0.81 | ALOX15 (0.46) | ALOX15CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL11077055 | 0.76 | CYP4F2 (0.42) | ALOX15CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL8160225 | 0.75 | ALDH1A1 (0.46) | ALOX15CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL3881192 | 0.73 | CYP4F2 (0.44) | ALOX15CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL6900414 | 0.72 | PKM (0.41) | ALOX15CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL637901 | 0.72 | — | — | |
| SCHEMBL776033 | 0.71 | PKM (0.44) | ALOX15CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL4187876 | 0.71 | ALOX15 (0.50) | ALOX15CYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL9588358 | 0.71 | CYP4F2 (0.42) | ALOX15CYP4F2CYP4A11ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965798-B1 | USEFUL MONOBACTAM ANTIBIOTICS | BASILEA PHARMACEUTICA AG (CH) | 2011-10-19 | — | — | EP | disclosed |
| WO-2007065288-A2 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2007-06-14 | — | — | WO | disclosed |