Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13911836 | 0.83 | RIPK1 (0.42) | RIPK1TSHRHIF1ACYP2D6CA12 | |
| SCHEMBL18219781 | 0.81 | TSHR (0.52) | RIPK1TSHRHIF1ACYP2D6CA12 | |
| SCHEMBL20418994 | 0.77 | RIPK1 (0.70) | RIPK1TSHRHIF1ACYP2D6CA12 | |
| SCHEMBL8061739 | 0.74 | TSHR (0.52) | RIPK1TSHRHIF1ACYP2D6KMT2A | |
| SCHEMBL13690835 | 0.73 | TSHR (0.46) | TSHRHIF1ACYP2D6KMT2ACA12 | |
| SCHEMBL4362706 | 0.72 | TSHR (0.57) | TSHRHIF1ACYP2D6KMT2ACA12 | |
| SCHEMBL5792738 | 0.71 | KCNA5 (0.52) | TSHRHIF1ACYP2D6CA12CA2 | |
| SCHEMBL9705190 | 0.70 | MMP8 (0.53) | RIPK1TSHRHIF1ACYP2D6CA12 | |
| SCHEMBL14733727 | 0.70 | PDK1 (0.51) | TSHRKMT2AHSD17B10MAPTMEN1 | |
| SCHEMBL4839587 | 0.70 | TSHR (0.59) | TSHRHIF1ACYP2D6KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2031448-B1 | Method for developing a heat-sensitive lithographic printing plate using an aqueous alkaline developing solution | AGFA GRAPHICS NV (BE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2009027272-A1 | A METHOD FOR DEVELOPING A PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2009-03-05 | — | — | WO | disclosed |