Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18404024 | 0.85 | EPHX2 (0.50) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL15003212 | 0.85 | POLB (0.50) | MAPTRAB9AL3MBTL1MEN1HTT | |
| SCHEMBL12058566 | 0.83 | ALDH1A1 (0.53) | MAPTHPGDRAB9AMEN1ALDH1A1 | |
| SCHEMBL13719675 | 0.80 | MEN1 (0.55) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL23139766 | 0.79 | NLRP3 (0.47) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL14540199 | 0.79 | CA1 (0.66) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL25776211 | 0.78 | PDK1 (0.50) | PDK1PDK2PDK3PDK4MMP8 | |
| SCHEMBL12920838 | 0.77 | PTPRC (0.54) | MAPTHPGDGAARAB9AL3MBTL1 | |
| SCHEMBL14997247 | 0.75 | MAPT (0.46) | PDK1PDK2PDK3PDK4MMP8 | |
| SCHEMBL14849461 | 0.75 | PDK1 (0.63) | PDK1PDK2PDK3PDK4MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1552923-B1 | Lithographic printing plate precursor and lithographic printing method using the same | FUJIFILM CORP (JP) | 2017-11-15 | — | — | EP | disclosed |
| US-20140296476-A1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | PROLYNX LLC | 2014-10-02 | — | — | US | disclosed |
| US-8722310-B2 | Lithographic printing plate precursor and method of preparing lithographic printing plate using the same | FUJIFILM CORPORATION (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722310-B2 | Lithographic printing plate precursor and method of preparing lithographic printing plate using the same | FUJIFILM CORPORATION (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20130052586-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE USING THE SAME | FUJIFILM CORPORATION (JP) | 2013-02-28 | — | — | US | disclosed |
| US-20130052586-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE USING THE SAME | FUJIFILM CORPORATION (JP) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296476-A1 | PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES | ABCB1, ABCB11, DNPEP | PDK1 2307/4885PDK2 3224/4885PDK3 3609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.