SCHEMBL12206604

SCHEMBL12206604

Cc1ccc2ccc3c(C)cc(N(c4ccccc4)c4ccc5oc6ccccc6c5c4)c4ccc1c2c34

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.36
HPGD P15428 4/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A2 P05177 1/20 0.34
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
AHR P35869 2/20 0.31
LMNA P02545 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12206602 0.93 MAOA (0.41) MAOAHPGDALDH1A1L3MBTL1CYP1A2
SCHEMBL18798575 0.86 KDM4E (0.38) MAOAHPGDALDH1A1TSHRHSD17B10
SCHEMBL22788095 0.86 MAPT (0.40) HPGDALDH1A1TSHRHSD17B10TDP1
SCHEMBL16237240 0.86 MAPT (0.40) HPGDALDH1A1TSHRHSD17B10TDP1
SCHEMBL2518484 0.86 MAPT (0.40) HPGDALDH1A1TSHRHSD17B10TDP1
SCHEMBL18798577 0.86 MAPT (0.40) HPGDALDH1A1TSHRHSD17B10TDP1
SCHEMBL21515766 0.85 MAOB (0.36) MAOAHPGDALDH1A1TSHRHSD17B10
SCHEMBL18101535 0.84 KDM4E (0.35) MAOAHPGDALDH1A1TSHRHSD17B10
SCHEMBL12206540 0.83 HPGD (0.38) MAOAHPGDALDH1A1CYP3A4TSHR
SCHEMBL12206340 0.83 ALOX5 (0.41) HPGDALDH1A1CYP3A4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11046667-B2 Aromatic amine derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-06-29 US disclosed
US-10570113-B2 Aromatic amine derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-02-25 US disclosed
US-20190071411-A1 AROMATIC AMINE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-07 US disclosed
US-20110248246-A1 AROMATIC AMINE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-10-13 US disclosed
US-20110248246-A1 AROMATIC AMINE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110248246-A1 AROMATIC AMINE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE AHR, ADRA1A, ADRA1D MAOA 260/4885HPGD 2295/4885ALDH1A1 49/4885
US-20190071411-A1 AROMATIC AMINE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE AHR, ADRA1A, ADRA1D MAOA 260/4885HPGD 2295/4885ALDH1A1 49/4885
US-10570113-B2 Aromatic amine derivative, light-emitting element, light-emitting device, electronic device, and lighting device AHR, ADRA1A, ADRA1D MAOA 250/4885HPGD 2256/4885ALDH1A1 48/4885
US-11046667-B2 Aromatic amine derivative, light-emitting element, light-emitting device, electronic device, and lighting device AHR, ADRA1A, ADRA1D MAOA 260/4885HPGD 2295/4885ALDH1A1 49/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.