SCHEMBL12207668

SCHEMBL12207668

CC1(C)c2ccccc2-c2ccc(-c3cccc4nc(-c5ccc(N(c6ccccc6)c6ccc(N(c7ccccc7)c7ccccc7)cc6)cc5)c(-c5ccc(N(c6ccccc6)c6ccc(N(c7ccccc7)c7ccccc7)cc6)cc5)nc34)cc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.33
KMT2A Q03164 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.33
KDM4E B2RXH2 6/20 0.33
LMNA P02545 5/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PSMB5 P28074 1/20 0.33
PIM1 P11309 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
L3MBTL1 Q9Y468 5/20 0.32
GAA P10253 2/20 0.32
PDE10A Q9Y233 1/20 0.32
HTT P42858 2/20 0.32
RXFP1 Q9HBX9 1/20 0.32
THRB P10828 1/20 0.32
NPSR1 Q6W5P4 2/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12207288 0.99 TDP1 (0.35) ALDH1A1KMT2ATDP1HPGDMEN1
SCHEMBL12207305 0.92 TDP1 (0.35) ALDH1A1KMT2ATDP1HPGDMEN1
SCHEMBL12564882 0.92 PDK2 (0.34) ALDH1A1HPGDKDM4ELMNASMN1; SMN2
SCHEMBL12207676 0.92 PDK2 (0.34) ALDH1A1HPGDKDM4ELMNASMN1; SMN2
SCHEMBL12690696 0.91 PDK2 (0.34) ALDH1A1HPGDKDM4ELMNASMN1; SMN2
SCHEMBL12207337 0.91 ADK (0.34) ALDH1A1TDP1HPGDKDM4ELMNA
SCHEMBL6725085 0.91 ADK (0.34) ALDH1A1TDP1HPGDKDM4ELMNA
SCHEMBL12146777 0.90 ALDH1A1 (0.40) ALDH1A1KMT2ATDP1HPGDMEN1
SCHEMBL6724999 0.90 ALDH1A1 (0.40) ALDH1A1KMT2ATDP1HPGDMEN1
SCHEMBL12207325 0.90 ALDH1A1 (0.40) ALDH1A1KMT2ATDP1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2004616-B1 QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING THE QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2014-05-21 EP disclosed
US-8471017-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO. LTD. (JP) 2013-06-25 US disclosed
US-8471017-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO. LTD. (JP) 2013-06-25 US disclosed
US-20110248254-A1 QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING THE QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-10-13 US disclosed
US-20110248254-A1 QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING THE QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-10-13 US disclosed
US-8008489-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-08-30 US disclosed
US-8008489-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-08-30 US disclosed
US-20100141130-A1 QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING THE QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-10 US disclosed
US-20100141130-A1 QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING THE QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-10 US disclosed
US-7696348-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORIES CO., LTD. (JP) 2010-04-13 US disclosed
US-7696348-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORIES CO., LTD. (JP) 2010-04-13 US disclosed
WO-2007108403-A1 QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING THE QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-27 WO disclosed
US-20070222374-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-27 US disclosed
US-20070222374-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100141130-A1 QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING THE QUINOXALINE DERIVATIVE NDUFA9, MT-ND1, NQO2 ALDH1A1 322/4885KMT2A 1975/4885TDP1 1195/4885
US-20070222374-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, electronic device using the quinoxaline derivative NDUFA9, MT-ND1, NQO2 ALDH1A1 322/4885KMT2A 1975/4885TDP1 1195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.