SCHEMBL12225936

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Clonidine SCHEMBL5983	0.89	ADRA2A (1.00)	ADRA2AADRA2BADRA2CLMNAADRA1A
	SCHEMBL29374579	0.89	ADRA2C (0.65)	ADRA2AADRA2BADRA2CLMNAADRA1A
	Clonidine SCHEMBL9838990	0.87	ADRA2A (0.97)	ADRA2AADRA2BADRA2CLMNAADRA1A
	Clonidine SCHEMBL2231324	0.87	ADRA2A (1.00)	ADRA2AADRA2BADRA2CLMNAADRA1A
	Clonidine SCHEMBL40752	0.87	ADRA2A (1.00)	ADRA2AADRA2BADRA2CLMNAADRA1A
	Clonidine SCHEMBL613364	0.87	ADRA2A (0.97)	ADRA2AADRA2BADRA2CLMNAADRA1A
	SCHEMBL9920135	0.82	ADRA2A (0.79)	ADRA2AADRA2BADRA2CLMNAADRA1A
	SCHEMBL11176814	0.82	ADRA2A (0.79)	ADRA2AADRA2BADRA2CLMNAADRA1A
	Clonidine SCHEMBL18050245	0.81	ADRA2A (0.82)	ADRA2AADRA2BADRA2CLMNAADRA1A
	SCHEMBL29352531	0.80	ADRA2A (0.81)	ADRA2AADRA2BADRA2CLMNAADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.