Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.50 |
| ▸ | RELA | Q04206 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195208 | 0.92 | NPC1 (0.59) | NPC1PTPN1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL15910010 | 0.92 | NPC1 (0.59) | NPC1PTPN1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL807727 | 0.92 | NPC1 (0.59) | NPC1PTPN1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL29353657 | 0.92 | NPC1 (0.62) | NPC1PTPN1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL39669 | 0.92 | NPC1 (0.62) | NPC1PTPN1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL17920176 | 0.92 | NPC1 (0.62) | NPC1PTPN1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL17571546 | 0.87 | TSHR (0.59) | NPC1PTPN1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL13938599 | 0.86 | NPC1 (0.61) | NPC1PTPN1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL12997145 | 0.86 | NPC1 (0.54) | NPC1PTPN1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL12997352 | 0.86 | NPC1 (0.54) | NPC1PTPN1SMN1; SMN2TP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044123-B2 | Ultraviolet absorber composition and resin composition | FUJIFILM CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |
| US-8044123-B2 | Ultraviolet absorber composition and resin composition | FUJIFILM CORPORATION (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20110077330-A1 | POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME | FUJIFILM CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |
| US-20100324181-A1 | ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20100324181-A1 | ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20100311877-A1 | NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100311877-A1 | NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311877-A1 | NOVEL TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION | AVPR1B, H1-0, H1-2 | NPC1 3106/4885PTPN1 4614/4885SMN1; SMN2 3996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.