Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11910278 | 0.79 | BRD4 (0.40) | KDM4ETSHRHTTBRD4BRD2 | |
| SCHEMBL19229871 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HTTSQOR | |
| SCHEMBL12204551 | 0.77 | METAP2 (0.50) | KDM4ETSHRALDH1A1HSD17B10HTT | |
| SCHEMBL9258894 | 0.74 | KDM4E (0.50) | KDM4ETSHRALDH1A1HSD17B10HTT | |
| SCHEMBL30022592 | 0.73 | KDM4E (0.48) | KDM4ETSHRALDH1A1HSD17B10HTT | |
| SCHEMBL8500242 | 0.71 | KDM4E (0.50) | KDM4ETSHRALDH1A1HSD17B10HTT | |
| SCHEMBL19398822 | 0.68 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10HTTBRD4 | |
| SCHEMBL14821700 | 0.68 | HSP90AA1 (0.49) | KDM4ETSHRTRPV1SQORABL1 | |
| SCHEMBL30178546 | 0.68 | HSP90AA1 (0.49) | KDM4ETSHRTRPV1SQORABL1 | |
| SCHEMBL7915750 | 0.68 | ALDH1A1 (0.55) | KDM4ETSHRALDH1A1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251391-A1 | Preparation of luminescent iridium complexes and precursors thereof | NATIONAL CHENG KUNG UNIVERSITY (TW) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251391-A1 | Preparation of luminescent iridium complexes and precursors thereof | SLC5A11, RUVBL2, CCRL2 | KDM4E 3965/4885TSHR 494/4885ALDH1A1 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.