Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.66 |
| ▸ | AR | P10275 | 4/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223217 | 0.86 | PGR (0.66) | PGRARNR3C1NR3C2 | |
| SCHEMBL1223621 | 0.82 | PGR (0.61) | PGRARNR3C1NR3C2 | |
| SCHEMBL62719 | 0.80 | PGR (1.00) | PGRARNR3C1NR3C2 | |
| SCHEMBL3883683 | 0.75 | PGR (0.86) | PGRARNR3C1NR3C2 | |
| SCHEMBL1222341 | 0.75 | PGR (0.67) | PGRARNR3C1NR3C2 | |
| SCHEMBL3872645 | 0.73 | PGR (1.00) | PGRARNR3C1NR3C2 | |
| SCHEMBL3876145 | 0.72 | PGR (1.00) | PGRARNR3C1NR3C2 | |
| SCHEMBL3870802 | 0.72 | PGR (1.00) | PGRARNR3C1NR3C2 | |
| SCHEMBL3876137 | 0.72 | PGR (1.00) | PGRARNR3C1NR3C2 | |
| SCHEMBL4179192 | 0.72 | PGR (0.82) | PGRARNR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476262-B2 | Cyanopyrroles | WYETH LLC (US) | 2013-07-02 | — | — | US | claimed |
| US-20110039839-A1 | Cyanopyrroles | WYETH LLC (US) | 2011-02-17 | — | — | US | claimed |
| CN-1133635-C | Cyanopyrroles for binding progesterone receptors | �Ʒ� | 2004-01-07 | — | — | CN | claimed |
| US-8476262-B2 | Cyanopyrroles | WYETH LLC (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110039839-A1 | Cyanopyrroles | WYETH LLC (US) | 2011-02-17 | — | — | US | disclosed |
| EP-1173433-B1 | CYANOPYRROLES AS PROGESTERONE RECEPTOR AGONISTS | WYETH CORP (US) | 2005-12-28 | — | — | EP | disclosed |
| CN-1133635-C | Cyanopyrroles for binding progesterone receptors | �Ʒ� | 2004-01-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039839-A1 | Cyanopyrroles | PGR, MC2R, THRB | PGR 1/4885AR 28/4885NR3C1 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.