SCHEMBL12232168

SCHEMBL12232168

C1=CC2C=NC=C(c3cc(-c4ccc(-c5cc(-c6cncc7ccccc67)cc(-c6cncc7ccccc67)c5)c(-c5nc6ccccc6o5)c4)cc(-c4cncc5ccccc45)c3)C2C=C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 2/20 0.35
PTGS2 P35354 3/20 0.34
ALDH1A1 P00352 5/20 0.33
HPGD P15428 4/20 0.33
MAPT P10636 3/20 0.33
KDM4E B2RXH2 3/20 0.33
MET P08581 1/20 0.33
USP2 O75604 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 4/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 2/20 0.31
TP53 P04637 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
CASP1 P29466 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12232167 0.98 PRKCZ (0.34) PRKCZPTGS2ALDH1A1HPGDMAPT
SCHEMBL15314932 0.83 ALDH1A1 (0.45) PRKCZPTGS2ALDH1A1HPGDMAPT
SCHEMBL15314931 0.80 ALDH1A1 (0.44) PRKCZPTGS2ALDH1A1HPGDMAPT
SCHEMBL12232166 0.75 ALDH1A1 (0.47) PRKCZPTGS2ALDH1A1HPGDMAPT
SCHEMBL12232163 0.74 ALDH1A1 (0.50) PRKCZALDH1A1HPGDMAPTKDM4E
SCHEMBL12232162 0.74 ALDH1A1 (0.50) PRKCZALDH1A1HPGDMAPTKDM4E
SCHEMBL12232161 0.73 ALDH1A1 (0.51) PRKCZALDH1A1HPGDMAPTKDM4E
SCHEMBL12232165 0.70 ALDH1A1 (0.43) PRKCZPTGS2ALDH1A1HPGDMAPT
SCHEMBL12203224 0.69 ALDH1A1 (0.51) PRKCZPTGS2ALDH1A1HPGDMAPT
SCHEMBL12232164 0.68 ALDH1A1 (0.46) PRKCZALDH1A1HPGDMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110260153-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-10-27 US disclosed
US-20110260153-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110260153-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME PPOX, AOX1, OR10J3 PRKCZ 3991/4885PTGS2 2414/4885ALDH1A1 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.