Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135394 | 0.98 | ALDH1A1 (0.48) | ALDH1A1MAPK1IDO1TDO2SMN1; SMN2 | |
| SCHEMBL29427056 | 0.98 | ALDH1A1 (0.48) | ALDH1A1MAPK1IDO1TDO2SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL3178489 | 0.95 | ALDH1A1 (0.46) | ALDH1A1MAPK1IDO1TDO2SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27726646 | 0.95 | ALDH1A1 (0.46) | ALDH1A1MAPK1IDO1TDO2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3176977 | 0.93 | IDO1 (0.48) | ALDH1A1MAPK1IDO1TDO2SMN1; SMN2 | |
| Methoxymethane SCHEMBL27727083 | 0.91 | HDAC4 (0.48) | ALDH1A1MAPK1IDO1TDO2SMN1; SMN2 | |
| SCHEMBL3171406 | 0.86 | SMN1; SMN2 (0.40) | ALDH1A1MAPK1IDO1TDO2SMN1; SMN2 | |
| SCHEMBL27794458 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPK1IDO1TDO2SMN1; SMN2 | |
| SCHEMBL25914832 | 0.85 | RXRA (0.51) | ALDH1A1MAPK1SMN1; SMN2HDAC4HDAC8 | |
| SCHEMBL27661944 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2HDAC4HDAC8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888464-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-02-15 | — | — | US | disclosed |
| US-20090274648-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090274648-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, HCCS, PYGL | ALDH1A1 623/4885MAPK1 3159/4885IDO1 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.