Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519966 | 0.98 | ALDH1A1 (0.69) | ALDH1A1HTTHRH3SMN1; SMN2POLB | |
| SCHEMBL13495500 | 0.84 | ALDH1A1 (0.69) | ALDH1A1HTTHRH3SMN1; SMN2POLB | |
| SCHEMBL10240068 | 0.84 | ALDH1A1 (0.63) | ALDH1A1HTTHRH3SMN1; SMN2POLB | |
| SCHEMBL13293320 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HTTHRH3SMN1; SMN2POLB | |
| SCHEMBL30309452 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HTTSMN1; SMN2KDM4ECHKA | |
| SCHEMBL22164021 | 0.83 | LMNA (0.60) | ALDH1A1HTTKDM4EPRMT6CHKA | |
| SCHEMBL18491483 | 0.83 | HRH3 (0.54) | ALDH1A1HTTHRH3SMN1; SMN2KDM4E | |
| SCHEMBL2960118 | 0.83 | CXCR4 (0.50) | ALDH1A1HTTHRH3TDP1 | |
| Hydrochloric Acid SCHEMBL7401709 | 0.82 | ALDH1A1 (0.96) | ALDH1A1HTTHRH3SMN1; SMN2POLB | |
| SCHEMBL28366319 | 0.82 | ALDH1A1 (0.60) | ALDH1A1HTTHRH3SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR55, NR1H2 | ALDH1A1 2341/4885HTT 2791/4885HRH3 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.