Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | DCK | P27707 | 6/20 | 0.33 |
| ▸ | EP300 | Q09472 | 4/20 | 0.33 |
| ▸ | POLG | P54098 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27798766 | 0.84 | ALB (0.39) | ALBDCKEP300POLGCDK4 | |
| SCHEMBL1739594 | 0.82 | ALB (0.38) | ALBDCKEP300POLGCDK4 | |
| SCHEMBL1223946 | 0.79 | ALB (0.38) | ALBDCKEP300POLGCDK4 | |
| SCHEMBL12883793 | 0.78 | EP300 (0.38) | ALBDCKEP300 | |
| SCHEMBL2221563 | 0.78 | ALB (0.39) | ALBDCKEP300POLG | |
| SCHEMBL1224575 | 0.76 | CES2 (0.36) | ALBDCKEP300CDK4CDK2 | |
| SCHEMBL1224879 | 0.76 | EP300 (0.46) | ALBEP300 | |
| SCHEMBL3627806 | 0.76 | DCK (0.43) | DCKEP300CDK4CDK2 | |
| SCHEMBL12884079 | 0.74 | ALB (0.34) | ALBDCKEP300 | |
| SCHEMBL12882192 | 0.74 | KMT2A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462133-B1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-24 | — | — | EP | disclosed |
| US-8318758-B2 | 5-fluoro-2-oxopyrimidine-1(2H)-carboxylate derivatives | DOW AGROSCIENCES, LLC (US) | 2012-11-27 | — | — | US | disclosed |
| EP-2462133-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | Dow AgroSciences LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2011-02-10 | — | — | US | disclosed |
| WO-2011017544-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | DDT, PFAS, CASP2 | ALB 4445/4885DCK 335/4885EP300 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.