Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | DHPS | P49366 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222964 | 0.89 | GAA (0.39) | HSP90AA1HSP90AB1DHPSRAB9ALMNA | |
| SCHEMBL1397064 | 0.89 | DHPS (0.43) | GRK6HSP90AA1HSP90AB1DHPSRAB9A | |
| SCHEMBL1477814 | 0.86 | TDP1 (0.38) | LMNAKMODPP4 | |
| SCHEMBL27911272 | 0.83 | GRK6 (0.39) | GRK6HSP90AA1HSP90AB1DHPSRAB9A | |
| SCHEMBL1918041 | 0.81 | GAA (0.38) | HSP90AA1HSP90AB1DHPSRAB9ALMNA | |
| SCHEMBL27911271 | 0.81 | TNFSF11 (0.36) | GRK6HSP90AA1HSP90AB1DHPSRAB9A | |
| SCHEMBL2464538 | 0.81 | GRK6 (0.38) | GRK6HSP90AA1HSP90AB1RAB9ALMNA | |
| SCHEMBL2469994 | 0.81 | HSP90AA1 (0.42) | GRK6HSP90AA1HSP90AB1RAB9ALMNA | |
| SCHEMBL1478092 | 0.80 | TDP1 (0.36) | MAPK1KMOSMN1; SMN2ALDH1A1 | |
| SCHEMBL1397063 | 0.80 | DHPS (0.40) | DHPSKMOKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102977036-A | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES LLC | 2013-03-20 | — | — | CN | disclosed |
| US-7888287-B2 | 6-Amino-5-chloro-2-(4-chloro-2,6-difluoro-3-methoxy-phenyl)pyrimidine-4-carboxylic Acid Methyl Ester; preemergence herbicides; applying to the soil in rice fields; broad spectrum of weed control against woody plants, grasses and sedges as well as broadleafs | DOW AGROSCIENCES LLC (US) | 2011-02-15 | — | — | US | disclosed |
| EP-1971579-B1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-28 | — | — | EP | disclosed |
| US-20090149329-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (IN) | 2009-06-11 | — | — | US | disclosed |
| US-7538214-B2 | 2-(poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2009-05-26 | — | — | US | disclosed |
| EP-1971579-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2008-09-24 | — | — | EP | disclosed |
| US-20080091016-A1 | 2-(Poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-04-17 | — | — | US | disclosed |
| US-7300907-B2 | 2-(Poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2007-11-27 | — | — | US | disclosed |
| US-20070179059-A1 | 2-(Poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2007-08-02 | — | — | US | disclosed |
| WO-2007082076-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149329-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DDT, DDC, HDHD5 | GRK6 1047/4885HSP90AA1 1128/4885HSP90AB1 1410/4885 |
| US-20080091016-A1 | 2-(Poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DDT, DDC, HDHD5 | GRK6 1047/4885HSP90AA1 1128/4885HSP90AB1 1410/4885 |
| US-20070179059-A1 | 2-(Poly-substituted aryl)-6-amino-5-halo-4-pyrimidinecarboxylic acids and their use as herbicides | DDT, DDC, HDHD5 | GRK6 1047/4885HSP90AA1 1128/4885HSP90AB1 1410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.