Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | KIF5C | O60282 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | KIF5A | Q12840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1480091 | 0.86 | ALPL (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1477814 | 0.85 | TDP1 (0.38) | TDP1KMOKEAP1NFE2L2CDK4 | |
| SCHEMBL1477987 | 0.83 | GRM2 (0.42) | TDP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16075508 | 0.82 | PRKAB2 (0.38) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL1224322 | 0.80 | GRK6 (0.38) | KMOALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1477753 | 0.80 | KMO (0.50) | TDP1KMOALDH1A1MAPK1CDK2 | |
| SCHEMBL1477157 | 0.79 | TDP1 (0.36) | TDP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16075500 | 0.79 | CYP3A4 (0.36) | TDP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16075503 | 0.78 | TDP1 (0.41) | TDP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16072639 | 0.78 | TDP1 (0.33) | TDP1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598085-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | claimed |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | claimed |
| US-8357633-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC (US) | 2013-01-22 | — | — | US | claimed |
| EP-2573074-B1 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4- pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2014-07-23 | — | — | EP | disclosed |
| US-8598085-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | disclosed |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | disclosed |
| EP-2573074-A1 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4- pyrimidinecarboxylates and their use as herbicides | Dow AgroSciences LLC (US) | 2013-03-27 | — | — | EP | disclosed |
| US-8357633-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC (US) | 2013-01-22 | — | — | US | disclosed |
| EP-2176239-B1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2311815-B1 | 2-(2-Fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2311815-A1 | 2-(2-Fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidine carboxylates and their use as herbicides | Dow AgroSciences LLC (US) | 2011-04-20 | — | — | EP | disclosed |
| US-7915200-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2011-03-29 | — | — | US | disclosed |
| US-20100120621-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-05-13 | — | — | US | disclosed |
| EP-2176239-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009023438-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090048109-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120621-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | TDP1 1320/4885PRKAB2 3252/4885PRKAG1 3204/4885 |
| US-20090048109-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | TDP1 1366/4885PRKAB2 3294/4885PRKAG1 3293/4885 |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | TDP1 1320/4885PRKAB2 3252/4885PRKAG1 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.