SCHEMBL12246723

SCHEMBL12246723

Cc1cc(CCC(=O)NCCc2ccc(O)cc2)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
TRPV1 Q8NER1 2/20 0.53
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 2/20 0.53
F13A1 P00488 1/20 0.53
GAA P10253 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
GFER P55789 1/20 0.51
HCAR2 Q8TDS4 1/20 0.51
ESRRG P62508 2/20 0.50
ALOX12 P18054 1/20 0.49
ESRRB O95718 1/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
HPGD P15428 1/20 0.49
PTGS1 P23219 1/20 0.49
BLM P54132 1/20 0.49
HIF1A Q16665 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12246698 0.92 KMT2A (0.54) MAPTMEN1KMT2ATRPV1HSD17B10
SCHEMBL12246749 0.90 MAPT (0.65) MAPTMEN1KMT2ATRPV1HSD17B10
SCHEMBL2378518 0.87 TRPV1 (0.68) MAPTMEN1KMT2ATRPV1HSD17B10
SCHEMBL31363209 0.87 TRPV1 (0.68) MAPTMEN1KMT2ATRPV1HSD17B10
SCHEMBL2379821 0.85 KDM4E (0.65) MAPTKDM4EF13A1GAASMN1; SMN2
SCHEMBL10408493 0.84 KMT2A (0.61) MAPTKMT2AKDM4EF13A1GAA
SCHEMBL2376785 0.83 MEN1 (0.67) MEN1KMT2ATRPV1ALDH1A1
SCHEMBL17277242 0.82 GAA (0.65) MAPTMEN1KMT2ATRPV1HSD17B10
SCHEMBL19033146 0.82 MAPT (0.59) MAPTMEN1KMT2ATRPV1HSD17B10
SCHEMBL12246697 0.82 MAPT (0.65) MAPTMEN1KMT2ATRPV1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9089499-B2 Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) 2015-07-28 US disclosed
US-20130272983-A1 Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions Universite Joseph Fourier-Grenoble 1. (FR) 2013-10-17 US disclosed
US-8481593-B2 Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) 2013-07-09 US disclosed
US-20110237551-A1 Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) 2011-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237551-A1 Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions TYR, CUTA, HPD MAPT 3126/4885MEN1 3977/4885KMT2A 2137/4885
US-20130272983-A1 Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions TYR, CUTA, HPD MAPT 3115/4885MEN1 3994/4885KMT2A 2090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.