Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107219 | 0.91 | MAPT (0.71) | MAPTHSD17B10TRPV1MEN1KMT2A | |
| SCHEMBL12246723 | 0.90 | MAPT (0.53) | MAPTHSD17B10TRPV1MEN1KMT2A | |
| SCHEMBL12246698 | 0.90 | KMT2A (0.54) | MAPTHSD17B10TRPV1MEN1KMT2A | |
| SCHEMBL12246697 | 0.89 | MAPT (0.65) | MAPTHSD17B10TRPV1MEN1KMT2A | |
| SCHEMBL109158 | 0.86 | MAPT (0.73) | MAPTHSD17B10TRPV1MEN1KMT2A | |
| SCHEMBL2378518 | 0.85 | TRPV1 (0.68) | MAPTHSD17B10TRPV1MEN1KMT2A | |
| SCHEMBL31363209 | 0.85 | TRPV1 (0.68) | MAPTHSD17B10TRPV1MEN1KMT2A | |
| SCHEMBL3324677 | 0.84 | TRPV1 (0.84) | MAPTHSD17B10TRPV1MEN1KMT2A | |
| SCHEMBL8269764 | 0.84 | MAPT (0.79) | MAPTHSD17B10TRPV1MEN1KMT2A | |
| SCHEMBL10029412 | 0.84 | MAPT (0.70) | MAPTHSD17B10TRPV1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089499-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | Universite Joseph Fourier-Grenoble 1. (FR) | 2013-10-17 | — | — | US | disclosed |
| US-8481593-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) | 2013-07-09 | — | — | US | disclosed |
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | MAPT 3126/4885HSD17B10 31/4885TRPV1 1020/4885 |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | MAPT 3115/4885HSD17B10 31/4885TRPV1 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.