Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.81 |
| ▸ | TYR | P14679 | 1/20 | 0.81 |
| ▸ | APP | P05067 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 6/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.65 |
| ▸ | MMP1 | P03956 | 1/20 | 0.65 |
| ▸ | ARG1 | P05089 | 1/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.65 |
| ▸ | MMP9 | P14780 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16382867 | 1.00 | ACHE (0.81) | ACHETYRAPPMAPTALDH1A1 | |
| SCHEMBL17956820 | 0.93 | TYR (0.85) | ACHETYRAPPMAPTALDH1A1 | |
| SCHEMBL17956819 | 0.93 | TYR (0.85) | ACHETYRAPPMAPTALDH1A1 | |
| SCHEMBL12299133 | 0.93 | TYR (0.85) | ACHETYRAPPMAPTALDH1A1 | |
| SCHEMBL1917292 | 0.92 | MAPT (0.84) | ACHETYRMAPTALDH1A1KDM4E | |
| SCHEMBL1917252 | 0.92 | MAPT (0.84) | ACHETYRMAPTALDH1A1KDM4E | |
| SCHEMBL4812487 | 0.92 | MAPT (0.84) | ACHETYRMAPTALDH1A1KDM4E | |
| SCHEMBL31286546 | 0.92 | MAPT (0.84) | ACHETYRMAPTALDH1A1KDM4E | |
| SCHEMBL32679235 | 0.92 | MAPT (0.84) | ACHETYRMAPTALDH1A1KDM4E | |
| SCHEMBL32679236 | 0.92 | MAPT (0.84) | ACHETYRMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089499-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) | 2015-07-28 | — | — | US | disclosed |
| US-9089499-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | Universite Joseph Fourier-Grenoble 1. (FR) | 2013-10-17 | — | — | US | disclosed |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | Universite Joseph Fourier-Grenoble 1. (FR) | 2013-10-17 | — | — | US | disclosed |
| US-8481593-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) | 2013-07-09 | — | — | US | disclosed |
| US-8481593-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) | 2013-07-09 | — | — | US | disclosed |
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2011-09-29 | — | — | US | disclosed |
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2011-09-29 | — | — | US | disclosed |
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2007-08-09 | — | — | US | disclosed |
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | ACHE 1052/4885TYR 1/4885APP 2129/4885 |
| US-20070183996-A1 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | TYR, CUTA, HPD | ACHE 1070/4885TYR 1/4885APP 2180/4885 |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | ACHE 1070/4885TYR 1/4885APP 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.