Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12246783 | 0.96 | MAPT (0.56) | MAPTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL12299017 | 0.89 | MAPT (0.69) | MAPTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL12246751 | 0.84 | MAPT (0.56) | MAPTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL12246785 | 0.83 | MAPT (0.55) | MAPTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL12246744 | 0.78 | MAPT (0.76) | MAPTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL108280 | 0.78 | MAPT (0.60) | MAPTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL1917292 | 0.78 | MAPT (0.84) | MAPTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL1917252 | 0.78 | MAPT (0.84) | MAPTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL32679236 | 0.78 | MAPT (0.84) | MAPTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL4812487 | 0.78 | MAPT (0.84) | MAPTALDH1A1KDM4EPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089499-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | Universite Joseph Fourier-Grenoble 1. (FR) | 2013-10-17 | — | — | US | disclosed |
| US-8481593-B2 | Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions | BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) | 2013-07-09 | — | — | US | disclosed |
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237551-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | MAPT 3126/4885ALDH1A1 148/4885KDM4E 1240/4885 |
| US-20130272983-A1 | Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions | TYR, CUTA, HPD | MAPT 3115/4885ALDH1A1 150/4885KDM4E 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.