SCHEMBL12246779

SCHEMBL12246779

Cc1ccc(CCOC(=O)CCc2ccc(O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.58
TDP1 Q9NUW8 2/20 0.54
CYP4F2 P78329 1/20 0.53
CYP4A11 Q02928 1/20 0.53
MAPT P10636 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
ALOX5 P09917 1/20 0.51
LMNA P02545 1/20 0.51
MET P08581 4/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
SLC5A1 P13866 1/20 0.49
SLC5A2 P31639 1/20 0.49
TYR P14679 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12246766 0.92 APP (0.67) APPTDP1CYP4F2CYP4A11MAPT
SCHEMBL25456044 0.91 MET (0.48) APPTDP1MAPTALOX5LMNA
SCHEMBL22109660 0.88 TDP1 (0.53) APPTDP1CYP4F2CYP4A11MAPT
SCHEMBL17107198 0.88 TDP1 (0.68) APPTDP1CYP4F2CYP4A11MAPT
SCHEMBL19047031 0.86 APP (0.59) APPTDP1MAPTALOX5MET
SCHEMBL19047030 0.85 ALOX5 (0.56) APPTDP1CYP4F2CYP4A11MAPT
SCHEMBL21185857 0.85 TDP1 (0.50) APPTDP1CYP4F2CYP4A11MAPT
SCHEMBL11985733 0.85 TDP1 (0.59) APPTDP1CYP4F2CYP4A11MAPT
SCHEMBL22693977 0.84 MAPT (0.69) APPTDP1MAPTL3MBTL1ALOX5
SCHEMBL15153058 0.84 APP (0.62) APPTDP1CYP4F2CYP4A11MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481593-B2 Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) 2013-07-09 US disclosed
US-20110237551-A1 Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) 2011-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237551-A1 Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions TYR, CUTA, HPD APP 2129/4885TDP1 2072/4885CYP4F2 682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.