Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14245029 | 0.83 | HIF1A (0.32) | ALDH1A1HIF1AEPAS1MAPT | |
| SCHEMBL10146239 | 0.81 | MEN1 (0.39) | KMT2ACYP2A6ALDH1A1MEN1HIF1A | |
| SCHEMBL12246828 | 0.71 | ALDH1A1 (0.35) | KMT2AALDH1A1MAPT | |
| SCHEMBL23996388 | 0.69 | KMT2A (0.39) | KMT2AATMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1309456 | 0.68 | — | — | |
| SCHEMBL16270678 | 0.67 | SLC6A2 (0.39) | KMT2AATMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24671964 | 0.67 | SLC6A2 (0.39) | KMT2AATMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12629680 | 0.65 | KMT2A (0.36) | KMT2AATMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11932651 | 0.65 | TP53 (0.38) | KMT2AATMALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL9883870 | 0.64 | ALDH1A1 (0.59) | KMT2ACYP2A6CYP2D6ALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140051109-A1 | NOVEL COMPOUNDS WITH PHOTOLUMINESCENCE PROPERTIES AND APPLICATIONS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-02-20 | — | — | US | disclosed |
| WO-2012118444-A9 | NOVEL COMPOUNDS WITH PHOTOLUMINESCNCE PROPERTIES AND APPLICATIONS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-10-11 | — | — | WO | disclosed |
| WO-2012118444-A1 | NOVEL COMPOUNDS WITH PHOTOLUMINESCNCE PROPERTIES AND APPLICATIONS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-09-07 | — | — | WO | disclosed |
| US-8013149-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-09-06 | — | — | US | disclosed |
| US-8013149-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-09-06 | — | — | US | disclosed |
| US-20090270638-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-29 | — | — | US | disclosed |
| US-20090270638-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-29 | — | — | US | disclosed |
| US-7582751-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-09-01 | — | — | US | disclosed |
| US-7582751-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-09-01 | — | — | US | disclosed |
| WO-2007018808-A2 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027312-A1 | Methods and intermediates for the synthesis of porphyrins | PPOX, DHPS, POR | KMT2A 1827/4885CYP2A6 295/4885ATM 2477/4885 |
| US-20090270638-A1 | METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS | PPOX, DHPS, POR | KMT2A 1827/4885CYP2A6 295/4885ATM 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.