Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12247469 | 0.91 | KDM4E (0.33) | TSHR | |
| SCHEMBL12300025 | 0.90 | CYP3A4 (0.31) | CYP3A4TSHR | |
| SCHEMBL12299416 | 0.81 | FAAH (0.33) | — | |
| SCHEMBL779447 | 0.79 | CA2 (0.38) | — | |
| SCHEMBL12247470 | 0.76 | CA2 (0.41) | — | |
| SCHEMBL5555393 | 0.76 | — | — | |
| SCHEMBL4697072 | 0.73 | LMNA (0.39) | TSHR | |
| SCHEMBL18876671 | 0.73 | — | — | |
| SCHEMBL2304274 | 0.72 | CA2 (0.43) | TSHR | |
| SCHEMBL3121124 | 0.72 | CA2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230419-A1 | IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230419-A1 | IAP BINDING COMPOUNDS | BIRC5, BIRC7, BIRC3 | CYP3A4 3839/4885TSHR 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.