Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.74 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14852891 | 0.89 | OPRM1 (0.60) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14392904 | 0.87 | OPRM1 (0.71) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12948089 | 0.85 | OPRM1 (1.00) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13848156 | 0.84 | OPRM1 (0.54) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13431183 | 0.82 | OPRM1 (0.52) | OPRM1OPRD1OPRK1 | |
| SCHEMBL16015646 | 0.82 | OPRM1 (0.52) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14220696 | 0.78 | OPRM1 (0.49) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12257903 | 0.76 | OPRM1 (0.65) | OPRM1OPRD1OPRK1 | |
| SCHEMBL2738003 | 0.76 | OPRM1 (0.65) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13534483 | 0.75 | OPRM1 (0.81) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110262359-A1 | COMPOSITIONS COMPRISING ENZYME-CLEAVABLE PRODRUGS OF ACTIVE AGENTS AND INHIBITORS THEREOF | SIGNATURE THERAPEUTICS, INC. | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110262359-A1 | COMPOSITIONS COMPRISING ENZYME-CLEAVABLE PRODRUGS OF ACTIVE AGENTS AND INHIBITORS THEREOF | PEPD, TMPRSS15, ADAM17 | OPRM1 4091/4885OPRD1 4269/4885OPRK1 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.